EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …
Targeting adipose tissue in the treatment of obesity-associated diabetes
CM Kusminski, PE Bickel, PE Scherer - Nature reviews Drug discovery, 2016 - nature.com
Adipose tissue regulates numerous physiological processes, and its dysfunction in obese
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …
Photoacoustic molecular imaging-escorted adipose photodynamic–browning synergy for fighting obesity with virus-like complexes
R Chen, S Huang, T Lin, H Ma, W Shan, F Duan… - Nature …, 2021 - nature.com
Photodynamic therapy and adipose browning induction are two promising approaches to
reverse obesity. The former strategy acts rapidly and locally, whereas the latter has a more …
reverse obesity. The former strategy acts rapidly and locally, whereas the latter has a more …
Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues
V Pellegrinelli, S Carobbio, A Vidal-Puig - Diabetologia, 2016 - Springer
White adipose tissue (WAT) has key metabolic and endocrine functions and plays a role in
regulating energy homeostasis and insulin sensitivity. WAT is characterised by its capacity to …
regulating energy homeostasis and insulin sensitivity. WAT is characterised by its capacity to …
Immune regulation of metabolic homeostasis in health and disease
JR Brestoff, D Artis - Cell, 2015 - cell.com
Obesity is an increasingly prevalent disease worldwide. While genetic and environmental
factors are known to regulate the development of obesity and associated metabolic …
factors are known to regulate the development of obesity and associated metabolic …
Microbiota depletion promotes browning of white adipose tissue and reduces obesity
N Suárez-Zamorano, S Fabbiano, C Chevalier… - Nature medicine, 2015 - nature.com
Brown adipose tissue (BAT) promotes a lean and healthy phenotype and improves insulin
sensitivity. In response to cold or exercise, brown fat cells also emerge in the white adipose …
sensitivity. In response to cold or exercise, brown fat cells also emerge in the white adipose …
Heterogeneity of adipose tissue in development and metabolic function
T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …
compartmentalized into individual depots and distributed throughout the body. These …
MicroRNA regulatory networks in human adipose tissue and obesity
P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …
therefore, biological processes in different tissues. A major function of miRNAs in adipose …
Warming induces significant reprogramming of beige, but not brown, adipocyte cellular identity
Beige and brown adipocytes generate heat in response to reductions in ambient
temperature. When warmed, both beige and brown adipocytes exhibit morphological" …
temperature. When warmed, both beige and brown adipocytes exhibit morphological" …
The molecular mechanisms of obesity paradox
AS Antonopoulos, D Tousoulis - Cardiovascular research, 2017 - academic.oup.com
Clinical observations suggest a complex relationship between human obesity and
cardiovascular disease. Whilst abdominal (visceral) adiposity leads to deleterious metabolic …
cardiovascular disease. Whilst abdominal (visceral) adiposity leads to deleterious metabolic …