Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
[HTML][HTML] Designing nanoparticle-based drug delivery systems for precision medicine
J Yang, C Jia, J Yang - International journal of medical sciences, 2021 - ncbi.nlm.nih.gov
Traditional drugs are facing bottlenecks of lower solubility, absorption, and especially the
inefficient organs or cells targeting during the precision medicine era. It is urgently needed to …
inefficient organs or cells targeting during the precision medicine era. It is urgently needed to …
Quality by design (QbD) approach in processing polymeric nanoparticles loading anticancer drugs by high pressure homogenizer
Polymeric nanoparticles prepared using high pressure homogenizer (HPH) present some
unique challenges during manufacturing which can be better understood by application of …
unique challenges during manufacturing which can be better understood by application of …
Nanoemulsions: The rising star of antiviral therapeutics and nanodelivery system—Current status and prospects
JS Franklyne, PM Gopinath, A Mukherjee… - Current Opinion in …, 2021 - Elsevier
Nanoemulsions (NEs) of essential oil (EO) have significant potential to target
microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and …
microorganisms, especially viruses. They act as a vehicle for delivering antiviral drugs and …
The in vivo pharmacokinetics of block copolymers containing polyethylene glycol used in nanocarrier drug delivery systems
L Yin, Y Pang, L Shan, J Gu - Drug Metabolism and Disposition, 2022 - ASPET
Polyethylene glycol (PEG) is one of the most commonly used synthetic macromolecular
polymers for modifying small molecule drugs, peptides, proteins, or nanodrug delivery …
polymers for modifying small molecule drugs, peptides, proteins, or nanodrug delivery …
Nanotechnology-based approaches for emerging and re-emerging viruses: special emphasis on COVID-19
In recent decades, the major concern of emerging and re-emerging viral diseases has
become an increasingly important area of public health concern, and it is of significance to …
become an increasingly important area of public health concern, and it is of significance to …
[HTML][HTML] Monocytes as a convergent nanoparticle therapeutic target for cardiovascular diseases
D Aldarondo, E Wayne - Advanced drug delivery reviews, 2022 - Elsevier
Due to the increasing population of individuals with cardiovascular diseases and related
comorbidities, there is an increasing need for development of synergistic therapeutics …
comorbidities, there is an increasing need for development of synergistic therapeutics …
Development and validation of RP-HPLC method for quantification of repaglinide in mPEG-PCL polymeric nanoparticles: QbD-driven optimization, force degradation …
Repaglinide (REP) an insulinotropic agent used in the treatment of type-2 diabetes. It
belongs to meglitinides, which act by blocking the ATP sensitive potassium channels and …
belongs to meglitinides, which act by blocking the ATP sensitive potassium channels and …
Nanoparticle-based strategies to target HIV-infected cells
D Soundararajan, LN Ramana, P Shankaran… - Colloids and Surfaces B …, 2022 - Elsevier
Antiretroviral drugs employed for the treatment of human immunodeficiency virus (HIV)
infections have remained largely ineffective due to their poor bioavailability, numerous …
infections have remained largely ineffective due to their poor bioavailability, numerous …
Exploring the potential of intranasally administered naturally occurring quercetin loaded into polymeric nanocapsules as a novel platform for the treatment of anxiety
KY Mahmoud, NA Elhesaisy, AR Rashed… - Scientific Reports, 2023 - nature.com
Anxiety is one of the most prevalent forms of psychopathology that affects millions
worldwide. It gained more importance under the pandemic status that resulted in higher …
worldwide. It gained more importance under the pandemic status that resulted in higher …