Recombinational DNA repair is a universal aspect of DNA metabolism and is essential for
genomic integrity. It is a template-directed process that uses a second chromosomal copy …

Helicases and translocases are a ubiquitous, highly diverse group of proteins that perform
an extraordinary variety of functions in cells. Consequently, this review sets out to define a …

Using a combination of computer methods for iterative database searches and multiple
sequence alignment, we show that protein sequences related to the AAA family of ATPases …

Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

The efficient repair of double-strand breaks in DNA is critical for the maintenance of genome
stability and cell survival. Homologous recombination provides an efficient and faithful …

Although homologous recombination and DNA repair phenomena in bacteria were initially
extensively studied without regard to any relationship between the two, it is now appreciated …

SUMMARY The RecBCD enzyme of Escherichia coli is a helicase-nuclease that initiates the
repair of double-stranded DNA breaks by homologous recombination. It also degrades …

Four-way DNA intermediates, called Holliday junctions (HJs), can form during meiotic and
mitotic recombination, and their removal is crucial for chromosome segregation. A group of …

To reveal mechanisms of DNA damage checkpoint initiation, we structurally and
biochemically analyzed DisA, a protein that controls a Bacillus subtilis sporulation …

During site-specific DNA recombination, which brings about genetic rearrangement in
processes such as viral integration and excision and chromosomal segregation …