Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

Throughout development, the brain transits from early highly synchronous activity patterns to
a mature state with sparse and decorrelated neural activity, yet the mechanisms underlying …

Top-down prefrontal cortex inputs to the hippocampus have been hypothesized to be
important in memory consolidation, retrieval, and the pathophysiology of major psychiatric …

How the brain processes information accurately despite stochastic neural activity is a
longstanding question. For instance, perception is fundamentally limited by the information …

The brain continuously adapts its processing machinery to behavioural demands. To
achieve this, it rapidly modulates the operating mode of cortical circuits, controlling the way …

Advances in optical manipulation and observation of neural activity have set the stage for
widespread implementation of closed-loop and activity-guided optical control of neural …

Studies of visual processing in rodents have conventionally been performed on
anesthetized animals, precluding examination of the effects of behavior on visually evoked …

Linking neural microcircuit function to emergent properties of the mammalian brain requires
fine-scale manipulation and measurement of neural activity during behavior, where each …

Spatial navigation is often used as a behavioral task in studies of the neuronal circuits that
underlie cognition, learning and memory in rodents. The combination of in vivo microscopy …