The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …

The CYFIP1/SRA1 gene is located in a chromosomal region linked to various neurological
disorders, including intellectual disability, autism, and schizophrenia. CYFIP1 plays a dual …

The ocular lens is a model system for understanding important aspects of embryonic
development, such as cell specification and the spatiotemporally controlled formation of a …

Excitatory synapses are formed on dendritic spines, postsynaptic structures that change
during development and in response to synaptic activity. Once mature, however, spines can …

Genetic mutations of SHANK3 have been reported in patients with intellectual disability,
autism spectrum disorder (ASD) and schizophrenia. At the synapse, Shank3/ProSAP2 is a …

Neurodegeneration is the primary driver of disease progression in multiple sclerosis (MS)
resulting in permanent disability, creating an urgent need to discover its underlying …

Dendritic spines are small protrusions along dendrites where the postsynaptic components
of most excitatory synapses reside in the mature brain. Morphological changes in these actin …

WAVE1—the Wiskott–Aldrich syndrome protein (WASP)-family verprolin homologous
protein 1—is a key regulator of actin-dependent morphological processes in mammals …

Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic
component of most excitatory synapses in the brain. They play critical roles in synaptic …