[HTML][HTML] Cytokines in inflammatory disease

S Kany, JT Vollrath, B Relja - International journal of molecular sciences, 2019 - mdpi.com
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …

[HTML][HTML] Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine

C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …

[HTML][HTML] Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

A Alam, E Levanduski, P Denz, HS Villavicencio… - Cancer cell, 2022 - cell.com
TH 2 cells and innate lymphoid cells 2 (ILC2) can stimulate tumor growth by secreting pro-
tumorigenic cytokines such as interleukin-4 (IL-4), IL-5, and IL-13. However, the …

[HTML][HTML] Pattern recognition receptors and the host cell death molecular machinery

GP Amarante-Mendes, S Adjemian, LM Branco… - Frontiers in …, 2018 - frontiersin.org
Pattern Recognition Receptors (PRRs) are proteins capable of recognizing molecules
frequently found in pathogens (the so-called Pathogen-Associated Molecular Patterns …

Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

S Abraham Gnanadass, Y Divakar Prabhu… - Archives of Gynecology …, 2021 - Springer
Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

Interleukin‐33 (IL‐33): a nuclear cytokine from the IL‐1 family

C Cayrol, JP Girard - Immunological reviews, 2018 - Wiley Online Library
Summary Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family
abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both …

Emerging functions of IL-33 in homeostasis and immunity

GK Dwyer, LM D'Cruz… - Annual review of …, 2022 - annualreviews.org
Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …

[HTML][HTML] Epithelial cell–derived cytokines: more than just signaling the alarm

F Roan, K Obata-Ninomiya… - The Journal of clinical …, 2019 - Am Soc Clin Investig
The epithelial cell–derived cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25
are central regulators of type 2 immunity, which drives a broad array of allergic responses …

Interleukin-33 in health and disease

FY Liew, JP Girard, HR Turnquist - Nature Reviews Immunology, 2016 - nature.com
Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …

[HTML][HTML] The ST2/IL-33 axis in immune cells during inflammatory diseases

B Griesenauer, S Paczesny - Frontiers in immunology, 2017 - frontiersin.org
Il1rl1 (also known as ST2) is a member of the IL-1 superfamily, and its only known ligand is
IL-33. ST2 exists in two forms as splice variants: a soluble form (sST2), which acts as a …