Diabetic glomerulosclerosis is characterized by accumulation of extracellular matrix
proteins, mesangial expansion, and tubulointerstitial fibrosis. Hyperglycemia accelerates …

Glucose transport into mammalian cells is mediated by a group of glucose transporters
(GLUTs) on the plasma membrane. Human cytomegalovirus (HCMV)-infected human …

Diabetic kidney disease (DKD) affects∼ 40% of patients with diabetes and is associated
with high mortality rates. Among different cellular targets in DKD, podocytes, highly …

So far, case–control studies on the association between glucose transporter 1 (GLUT1)
gene single nucleotide polymorphisms (SNPs) and diabetic nephropathy (DN) have …

Extracellular purines act via P1 and P2 receptors on podocytes and may influence on their
function. This action may be modified under various (patho) physiological conditions leading …

Diabetes mellitus and its complications have become a major health concern in Western
countries. Increased activity of the intrarenal renin–angiotensin system (RAS) contributes to …

The prorenin receptor [(P) RR] is upregulated in the diabetic kidney and has been implicated
in the high glucose (HG)-induced overproduction of profibrotic molecules by mesangial cells …

Podocytes have an important role in the maintenance of glomerular capillary
architecture/function. Studies suggests that in glomerular diseases podocytes' damage often …

Background: Berberine plays a critical role of the glomerular mesangial cells (GMCs)
abnormal proliferation during diabetic nephropathy (DN). This study aims to explore the …

The prorenin receptor [(P) RR] is upregulated in the diabetic kidney and has been implicated
in the high glucose (HG)-induced overproduction of profibrotic molecules by mesangial cells …