Quantitative determination of the antimalarials artemether and lumefantrine in biological samples: A review

LA Resende, PHR da Silva, C Fernandes - Journal of Pharmaceutical and …, 2019 - Elsevier
Malaria is a worldwide health issue, with 216 million cases reported in 2016. Due to the
widespread resistance of Plasmodium falciparum to conventional drugs, the first line …

Determination of antimalarial drugs in pharmaceutical formulations and human blood by liquid chromatography: a review

EA Penna, JCQ de Souza, MAL de Oliveira… - Analytical …, 2021 - pubs.rsc.org
Malaria is a life-threatening disease being treated by oral medication. This is the best
treatment to reduce morbidity and mortality, prevent disease progression to the most severe …

Semisynthetic derivative of Artemisia annua-loaded transdermal bioadhesive for the treatment of uncomplicated malaria caused by Plasmodium falciparum in children

FV Zanutto, E McAlister, MMP Tangerina… - Journal of …, 2019 - Elsevier
According to the most recent World Health Organization statistics, malaria infected
approximately 219 million people in 2017, with an estimate of 435,000 deaths (World Health …

Effect of fresh pomegranate juice on the pharmacokinetic profile of artemether: An open-label, randomized, 2-period crossover study in healthy human volunteers

F Khuda, Z Iqbal, A Khan, MUK Sahibzada… - … of Pharmaceutical and …, 2021 - Elsevier
This study was designed to evaluate the effect of fresh pomegranate (Punica granatum L.)
juice on the pharmacokinetic profile of artemether in healthy volunteers. A randomized, open …

A sensitive, high‐throughput, and ecofriendly method for the determination of lumefantrine, artemether, and its active metabolite dihydroartemisinin by supercritical …

Y Yang, H Gao, S Hou, R Su, H Liu… - Journal of separation …, 2018 - Wiley Online Library
A quick and sensitive supercritical fluid chromatography with tandem mass spectrometry
method for the simultaneous determination of lumefantrine, artemether, and its active …

[PDF][PDF] A selective LC-MS/MS method for simultaneous quantification of Artemether, Lumefantrine and their principle metabolites in human plasma

MO ONGAS, E JUMA, CG KIRIMI, F OLOO… - ABC Res …, 2018 - academia.edu
We have developed and validated a sensitive, selective and reproducible reversed-phase
high-performance liquid chromatography method coupled with electrospray ionization mass …