Animals possess a wide variety of muscle types that support different kinds of movements.
Different muscles have distinct locations, morphologies and contractile properties, raising …

Skeletal muscle consists of bundles of myofibers containing millions of myofibrils, each of
which is formed of longitudinally aligned sarcomere structures. Sarcomeres are the …

Skeletal muscle function is impaired in heart failure patients due, in part, to loss of
myofibrillar protein content, in particular myosin. In the present study, we utilized small …

Striated muscle is an elegant system for study at many levels. Much has been learned about
the mechanism of contraction from studying the mechanical properties of intact and …

Transgenic Drosophila are highly useful for structure-function studies of muscle proteins.
However, our ability to mechanically analyze transgenically expressed mutant proteins in …

The average time myosin cross bridges remain bound to actin (t on) can be measured by
sinusoidal length perturbations (sinusoidal analysis) of striated muscle fibers using recently …

The mechanical properties of the honeybee's abdominal muscles endow its abdomen with
movement flexibility to perform various activities. However, the biomechanical properties of …

In skeletal muscle cells, myofibrillar proteins are highly organized into sarcomeres in which
thick filaments interdigitate with thin filaments to generate contractile force. The size of thick …

The indirect flight muscle (IFM) of insects is characterized by a near crystalline myofilament
lattice structure that likely evolved to achieve high power output. In Drosophila IFM, the …

The scaffold of striated muscle is predominantly comprised of myosin and actin polymers
known as thick filaments and thin filaments, respectively. The roles these filaments play in …