Circulating exosomes and exosomal microRNAs as biomarkers in gastrointestinal cancer

R Nedaeinia, M Manian, MH Jazayeri, M Ranjbar… - Cancer gene …, 2017 - nature.com
The most important biological function of exosomes is their possible use as biomarkers in
clinical diagnosis. Compared with biomarkers identified in conventional specimens such as …

Overcoming drug resistance in pancreatic cancer

J Long, Y Zhang, X Yu, J Yang, DG LeBrun… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Pancreatic cancer has the worst survival rate of all cancers. The current
standard care for metastatic pancreatic cancer is gemcitabine, however, the success of this …

Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer

M Stotz, A Gerger, F Eisner, J Szkandera… - British journal of …, 2013 - nature.com
Background: The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of
systemic inflammatory response. Previous findings from small-scale studies revealed …

[HTML][HTML] Survival in patients with primary liver cancer, gallbladder and extrahepatic biliary tract cancer and pancreatic cancer in Europe 1999–2007: results of …

C Lepage, R Capocaccia, M Hackl, V Lemmens… - European Journal of …, 2015 - Elsevier
Background The EUROCARE study collects and analyses survival data from population-
based cancer registries (CRs) in Europe in order to provide data on between-country …

[HTML][HTML] Role of gemcitabine-based combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials

D Ciliberto, C Botta, P Correale, M Rossi… - European journal of …, 2013 - Elsevier
BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer-related death
worldwide. Gemcitabine is the mainstay treatment for advanced disease. However, almost …

Association of the location of pancreatic ductal adenocarcinoma (head, body, tail) with tumor stage, treatment, and survival: a population-based analysis

FN van Erning, TM Mackay, LGM van der Geest… - Acta …, 2018 - Taylor & Francis
Background: The association between pancreatic ductal adenocarcinoma (PDAC) location
(head, body, tail) and tumor stage, treatment and overall survival (OS) is unclear. Methods …

Diabetes mellitus correlates with increased risk of pancreatic cancer: a population‐based cohort study in Taiwan

KF Liao, SW Lai, CI Li, WC Chen - Journal of gastroenterology …, 2012 - Wiley Online Library
Abstract Background and Aim: This study investigated whether diabetes mellitus (DM)
increased the risk of pancreatic cancer and whether anti‐diabetic drugs reduced the risk in …

Recent trends in survival of patients with pancreatic cancer in Germany and the United States

E Sirri, FA Castro, J Kieschke, L Jansen, K Emrich… - Pancreas, 2016 - journals.lww.com
Objectives Survival improvement for pancreatic cancer has not been observed in the last 4
decades. We report the most up-to-date population-based relative survival (RS) estimates …

[HTML][HTML] Systemic immune-inflammation index and changes of neutrophil-lymphocyte ratio as prognostic biomarkers for patients with pancreatic cancer treated with …

J Shang, X Han, H Zha, H Tao, X Li, F Yuan… - Frontiers in …, 2021 - frontiersin.org
The efficacy of current treatment regimens for pancreatic cancer (PC) remains unsatisfactory.
In recent years, immune checkpoint blockade (ICB) therapy has shown promising anti-tumor …

Pancreatic cancer: Wait times from presentation to treatment and survival in a population‐based study

V Jooste, O Dejardin, V Bouvier… - … journal of cancer, 2016 - Wiley Online Library
Pancreatic survival is one of the worst in oncology. To what extent wait times affect outcomes
in unknown No population‐based study has previously explored patient and treatment …