Abstract Purpose of Review To summarize the fundamental role of transforming growth
factor beta (TGFβ) signaling in osteocytes and highlight the physiological and …

Abstract Purpose of Review The integration of data from multiple genomic assays from
humans and non-human model organisms is an effective approach to identify genes …

Abstract Fibroblast growth factor 23 (FGF23) is a phosphate-regulating (Pi-regulating)
hormone produced by bone. Hereditary hypophosphatemic disorders are associated with …

Single-cell RNA-seq has led to novel designations for mesenchymal cells associated with
bone as well as multiple designations for what appear to be the same cell type. The main …

Single-cell RNA sequencing has led to numerous novel designations for mesenchymal cell
types associated with bone. Consequently, there are now multiple designations for what …

Breast cancer bone metastases increase fracture risk and are a major cause of morbidity
and mortality among women. Upon colonization by tumor cells, the bone microenvironment …

Sex is a biological variable important to consider in all biomedical experiments. However,
doing so in avian embryos can be challenging as sex can be morphologically …

摘要骨骼是动物机体重要部分, 在提供生物力学支持, 维持运动, 造血和钙稳态等方面发挥重要
作用. 普通转录组测序(bulk RNA sequencing, bulk RNA-seq) 在骨骼研究中的应用已为骨细胞 …

The availability of an open-access NIH-funded resource that shares bone-tissue-based
information obtained from patients with ROD with the broad scientific community represents …

Altered metabolism is a key contributor to pathology in numerous disease states, including
cancer. These changes can occur within certain pathological cells, or within a population of …