Pre-experimental studies in silico successfully used at various stages of the search and
optimization of the structures of biologically active compounds. The purpose of present …

The article presents the synthesis of 2-arylimino-4-methyl-2, 3-dihydro-1, 3-thiazoles via
Hantzsch reaction of thioureas and 3-chloropentane-2, 4-dione or ethyl 2-chloro-3 …

The aim of study was to determine of the parameters of the molecular structure of new 1-[2-
(R-phenylimino)-4-methyl-3-(3-[morpholine-4-yl] propyl)-2, 3-dihydro-1, 3-thiazol-5-yl] …

The synthesis of those new derivatives of 3-allyl-4-(R-phenyl)-N-(R1-phenyl)-thiazole-2-
imine was conducted which consist substituted aromatic radicals. Structure of the …

Experimental pharmacological research of 1-[2-(R-phenylimino)-4-methyl-3-(3-[morpholine-
4-yl] propyl)-2, 3dihydro-1, 3-thiazol-5-yl] ethane-1-one derivatives. Determination of the …

Search for angiotensin II receptor antagonists among 4-aryl-n-(aryl)-3-(prop-2-en-1-yl)-2,3-dihydro-1,3-thiazol-2-imine
derivati Page 1 Search for angiotensin II receptor antagonists among 4-aryl-n-(aryl)-3-(prop-2-en-1-yl)-2,3dihydro-1,3-thiazol-2-imine …

Background. QSAR analysis is an important tool for the identification of pharmacophore
fragments in biologically active substances and helps optimize the search for new effective …

The aim. Development of methods of quantitative determination of Cardiazol substance
using high-performance liquid chromatography. Materials and methods. The method of high …

New 4-aryl-3-(morpholin-4-yl)-2-arylimino-2, 3-dihydrothiazole derivatives 1.1-1.16 were
obtained using the Hantzsch reaction by condensation of N-(morpholin-4-yl)-N' …

An important step in the creation of potential drugs is to confirm the structure of the
synthesized compounds. This requires the use of modern physical and physicochemical …