Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance

V Melcher, M Graf, M Interlandi, N Moreno… - Acta …, 2020 - Springer
Atypical teratoid/rhabdoid tumors (ATRT) are known for their heterogeneity concerning
pathophysiology and outcome. However, predictive factors within distinct subgroups still …

Overall survival of primary intracranial atypical teratoid rhabdoid tumor following multimodal treatment: a pooled analysis of individual patient data

XJ Ma, D Li, L Wang, SY Hao, LW Zhang, JT Zhang… - Neurosurgical …, 2020 - Springer
No standard treatment protocol to guide the management of the primary central nervous
system atypical teratoid rhabdoid tumors (ATRTs). To evaluate the efficacy of GTR (gross …

[HTML][HTML] Inhibition of polo-like kinase 4 (PLK4): a new therapeutic option for rhabdoid tumors and pediatric medulloblastoma

ST Sredni, AW Bailey, A Suri, R Hashizume, X He… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Rhabdoid tumors (RT) are highly aggressive and vastly unresponsive embryonal tumors.
They are the most common malignant CNS tumors in infants below 6 months of age …

The forkhead box M1 (FOXM1) expression and antitumor effect of FOXM1 inhibition in malignant rhabdoid tumor

Y Shibui, K Kohashi, A Tamaki, I Kinoshita… - Journal of cancer …, 2021 - Springer
Purpose Malignant rhabdoid tumor (MRT) is a rare, highly aggressive sarcoma with an
uncertain cell of origin. Despite the existing standard of intensive multimodal therapy, the …

Pediatric Infratentorial Tumors' Treatment in the Molecular Era

MDS da Costa, CT Soares, VHC Betta, NS Silva… - 2024 - Springer
Background Central nervous system (CNS) tumors represent the primary type of solid tumor
in children, and for pediatric population, infratentorial location gains prominence. A new …

Intra-operative cerebrospinal fluid sampling versus post-operative lumbar puncture for detection of leptomeningeal disease in malignant paediatric brain tumours

SYY Low, CM Wei, KTE Chang, CY Huak, NL Ping… - Plos one, 2018 - journals.plos.org
Introduction Leptomeningeal disease is a feared sequelae of malignant paediatric brain
tumours. Current methods for its detection is the combined use of cranio-spinal MRI, and …

Embryonal Tumors: Atypical Teratoid/Rhabdoid Tumor (ATRT) Embryonal Tumors

S Weis, M Sonnberger, A Dunzinger… - Imaging Brain Diseases …, 2019 - Springer
Atypical teratoid/rhabdoid tumor (ATRT)(WHO grade IV) is a malignant CNS embryonal
tumor composed predominantly of poorly differentiated elements and frequently including …

Atypical Teratoid Rhabdoid Tumors

H Lindsay, A Huang - Oncology of CNS Tumors, 2019 - Springer
Atypical teratoid rhabdoid tumors (ATRTs) are highly malignant, heritable embryonal brain
tumors of infants and toddlers. They are characterized by diagnostic biallelic loss-of-function …