CD147 as a target for COVID-19 treatment: suggested effects of azithromycin and stem cell engagement
H Ulrich, MM Pillat - Stem cell reviews and reports, 2020 - Springer
The expressive number of deaths and confirmed cases of SARS-CoV-2 call for an urgent
demand of effective and available drugs for COVID-19 treatment. CD147, a receptor on host …
demand of effective and available drugs for COVID-19 treatment. CD147, a receptor on host …
CD147-spike protein interaction in COVID-19: Get the ball rolling with a novel receptor and therapeutic target
The combat against the Corona virus disease of 2019 (COVID-19), has created a chaos
among the healthcare institutions and researchers, in turn accelerating the dire need to …
among the healthcare institutions and researchers, in turn accelerating the dire need to …
Blood molecular markers associated with COVID‐19 immunopathology and multi‐organ damage
YM Chen, Y Zheng, Y Yu, Y Wang, Q Huang… - The EMBO …, 2020 - embopress.org
COVID‐19 is characterized by dysregulated immune responses, metabolic dysfunction and
adverse effects on the function of multiple organs. To understand host responses to COVID …
adverse effects on the function of multiple organs. To understand host responses to COVID …
Remodeling in asthma
S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …
in 2019. The disease is characterized by chronic airway inflammation, reversible …
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression
Allergic airway inflammation is characterized by marked in situ changes in gene and protein
expression, yet the role of microRNAs (miRNAs), a new family of key mRNA regulatory …
expression, yet the role of microRNAs (miRNAs), a new family of key mRNA regulatory …
Role of transforming growth factor–β in airway remodeling in asthma
R Halwani, S Al-Muhsen, H Al-Jahdali… - American journal of …, 2011 - atsjournals.org
TGF-β is one of the main mediators involved in tissue remodeling in the asthmatic lung. This
profibrotic cytokine is produced by a number of cells, including macrophages, epithelial …
profibrotic cytokine is produced by a number of cells, including macrophages, epithelial …
Bidirectional interaction of airway epithelial remodeling and inflammation in asthma
Asthma is a chronic disease of the airways that has long been viewed predominately as an
inflammatory condition. Accordingly, current therapeutic interventions focus primarily on …
inflammatory condition. Accordingly, current therapeutic interventions focus primarily on …
[HTML][HTML] Alternaria-derived serine protease activity drives IL-33–mediated asthma exacerbations
RJ Snelgrove, LG Gregory, T Peiró, S Akthar… - Journal of allergy and …, 2014 - Elsevier
Background The fungal allergen Alternaria alternata is implicated in severe asthma and
rapid onset life-threatening exacerbations of disease. However, the mechanisms that …
rapid onset life-threatening exacerbations of disease. However, the mechanisms that …
Airway remodelling in asthma: from benchside to clinical practice
C Bergeron, MK Tulic, Q Hamid - Canadian respiratory journal, 2010 - Wiley Online Library
Airway remodelling refers to the structural changes that occur in both large and small
airways relevant to miscellaneous diseases including asthma. In asthma, airway structural …
airways relevant to miscellaneous diseases including asthma. In asthma, airway structural …