The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Abstract Zinc transporter 3 (ZnT3) is the sole mechanism responsible for concentrating zinc
ions within synaptic vesicles in a subset of the brain's glutamatergic neurons. This vesicular …

Spinal cord injury (SCI) is accompanied by loss of Zn2+, which is an important cause of
glutamate excitotoxicity and death of local neurons as well as transplanted stem cells …

The molecular organization of ribbon synapses in photoreceptors and ON bipolar cells is
reviewed in relation to the process of neurotransmitter release. The interactions between …

The vast amount of fast excitatory neurotransmission in the mammalian central nervous
system is mediated by AMPA-subtype glutamate receptors (AMPARs). As a result, AMPAR …

Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …

Zinc is an essential nutrient for human health. It plays key roles in maintaining protein
structure and stability, serves as catalytic factor for many enzymes, and regulates diverse …

Synaptic zinc signaling modulates synaptic activity and is present in specific populations of
cortical neurons, suggesting that synaptic zinc contributes to the diversity of intracortical …

Zinc levels are high in ocular tissues and the distribution is non-uniform. Zinc is particularly
concentrated in the corneal epithelium and posterior stroma. Zinc is the most abundant trace …

Ionotropic glutamate receptors, such as NMDA, AMPA and kainate receptors, are ligand‐
gated ion channels that mediate much of the excitatory neurotransmission in the brain. Not …