Abstract Nrf2 (NFE2L2–nuclear factor (erythroid-derived 2)-like 2) is a transcription factor,
which is repressed by interaction with a redox-sensitive protein Keap1 (Kelch-like ECH …

Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are intimately associated with inflammation and overproduction of reactive …

Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

The prevalence of age-related diseases is in an upward trend due to increased life
expectancy in humans. Age-related conditions are among the leading causes of morbidity …

Nuclear factor-E2-related factor 2 (Nrf2) is a key transcription factor known to be involved in
maintaining cell redox balance and signal transduction and plays central role in reducing …

Alterations in the circadian system are characteristic of aging on Earth. With the decline in
physiological processes due to aging, several health concerns including vision loss …

The Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2
(Nrf2) pathway serves as a crucial regulator against oxidative stress (OS) damage in various …

Under normal physiological conditions, free radical generation and antioxidant defences are
balanced, and reactive oxygen species (ROS) usually act as secondary messengers in a …

Cells respond to stress by activating a variety of defense signaling pathways, including cell
survival and cell death pathways. Although cell survival signaling helps the cell to recover …

Cardiovascular diseases (CVD) are a group of cardiac and vascular disorders including
myocardial ischemia, congenital heart disease, heart failure, hypertension, atherosclerosis …