Cellular infiltration in traumatic brain injury

A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf… - Journal of …, 2020 - Springer
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

The role of markers of inflammation in traumatic brain injury

T Woodcock, MC Morganti-Kossmann - Frontiers in neurology, 2013 - frontiersin.org
Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …

Interactions of oxidative stress and neurovascular inflammation in the pathogenesis of traumatic brain injury

PM Abdul-Muneer, N Chandra, J Haorah - Molecular neurobiology, 2015 - Springer
Traumatic brain injury (TBI) is a major cause of death in the young age group and leads to
persisting neurological impairment in many of its victims. It may result in permanent …

[HTML][HTML] Involvement of pro-and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

JM Ziebell, MC Morganti-Kossmann - Neurotherapeutics, 2010 - Elsevier
Despite dramatic improvements in the management of traumatic brain injury (TBI), to date
there is no effective treatment available to patients, and morbidity and mortality remain high …

Interleukin-1 and interleukin-1 antagonism

CA Dinarello - 1991 - ashpublications.org
The polypeptide cytokine interleukin-1 (IL-1) affects nearly every tissue and organ system. IL-
1 is the prototype of the pro-inflammatory cytokines in that it induces the expression of a …

The pathogenesis of tuberculous meningitis

AG Davis, UK Rohlwink, A Proust… - Journal of leukocyte …, 2019 - academic.oup.com
Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

Central nervous system tuberculosis: pathogenesis and clinical aspects

RB Rock, M Olin, CA Baker, TW Molitor… - Clinical microbiology …, 2008 - Am Soc Microbiol
Tuberculosis of the central nervous system (CNS) is a highly devastating form of
tuberculosis, which, even in the setting of appropriate antitubercular therapy, leads to …

Bacterial meningitis in children

X Sáez-Llorens, GH McCracken - The lancet, 2003 - thelancet.com
This review comprises aspects of the epidemiology, microbiology, pathophysiology, clinical
manifestations, diagnosis, management, prognosis, and prevention of bacterial meningitis …

New perspectives on central and peripheral immune responses to acute traumatic brain injury

M Das, S Mohapatra, SS Mohapatra - Journal of neuroinflammation, 2012 - Springer
Traumatic injury to the brain (TBI) results in a complex set of responses involving various
symptoms and long-term consequences. TBI of any form can cause cognitive, behavioral …

Update on meningococcal disease with emphasis on pathogenesis and clinical management

M Van Deuren, P Brandtzaeg… - Clinical microbiology …, 2000 - Am Soc Microbiol
The only natural reservoir of Neisseria meningitidis is the human nasopharyngeal mucosa.
Depending on age, climate, country, socioeconomic status, and other factors, approximately …