Importance As cancer treatment has become more individualized, oncologic clinical trials
have become more complex. Increasingly numerous and stringent eligibility criteria …

Clinical trials are a critical component of evaluating the effectiveness of new medical
interventions and driving advancements in medical research. Therefore, timely enrollment of …

Importance Clinical trials play a critical role in the development of novel cancer therapies,
and precise estimates of the frequency with which older adult patients with cancer …

The process of developing new anticancer therapeutics has been considered by some to be
expensive, 1 time consuming, 2 bureaucratic, 3 and, to some extent, inefficient. 4 The …

Background Participant recruitment is a barrier to successful clinical research. One strategy
to improve recruitment is to conduct eligibility prescreening, a resource-intensive process …

Background Pharmaceutical product development relies on thorough and costly clinical
trials. Participant recruitment and monitoring can be challenging. The incorporation of cutting …

PURPOSE Tumor next-generation sequencing reports typically generate trial
recommendations for patients based on their diagnosis and genomic profile. However, these …

Objectives: Clinical Research Informatics (CRI) declares its scope in its name, but its
content, both in terms of the clinical research it supports—and sometimes initiates—and the …

Participant recruitment continues to be a challenge to the success of randomized controlled
trials, resulting in increased costs, extended trial timelines and delayed treatment …

Objective As clinical trials evolve in complexity, clinical trial data models that can capture
relevant trial data in meaningful, structured annotations and computable forms are needed …