[HTML][HTML] New insights into therapeutic applications and nanoformulation approaches of Hesperidin: An updated review

K Bansal, H Bhati, M Bajpai - Pharmacological Research-Modern …, 2024 - Elsevier
Introduction Hesperidin is a flavanone glycoside occurring in high levels in citrus species. It
is among the most significant natural anti-oxidants employed often in pharmaceuticals for …

Phytochemistry, pharmacological properties and pharmacokinetics of Citri Reticulatae Pericarpium: A systematic review

X Zhang, Y Jiang, J Zeng, X Li, H Xie, R Yang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Citri Reticulatae Pericarpium (CRP), known as
Chen Pi in China, is the most commonly used medicine for regulating qi. As a traditional …

[HTML][HTML] Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation

X Li, J Fu, M Guan, H Shi, W Pan… - Neural Regeneration …, 2024 - journals.lww.com
Previous studies have shown that Biochanin A, a flavonoid compound with estrogenic
effects, can serve as a neuroprotective agent in the context of cerebral ischemia/reperfusion …

Neuroprotective potential of hesperidin as therapeutic agent in the treatment of brain disorders: Preclinical evidence-based review

K Bansal, V Singh, S Singh… - Current Molecular …, 2024 - ingentaconnect.com
Neurodegenerative disorders (NDs) are progressive morbidities that represent a serious
health issue in the aging world population. There is a contemporary upsurge in worldwide …

Hesperidin guided injured spinal cord neural regeneration with a combination of MWCNT-collagen-hyaluronic acid composite: In-vitro analysis

M Raguraman, X Zhou, S Mickymaray… - International Journal of …, 2024 - Elsevier
Restoring the lost bioelectrical signal transmission along with the appropriate
microenvironment is one of the major clinical challenges in spinal cord regeneration. In the …

Therapeutic Potential and Clinical Evidence of Hesperidin as Neuroprotective Agent

S Joshi, AK Dhingra, B Chopra… - … System Agents in …, 2022 - ingentaconnect.com
Background: Neuroprotection is preserving neural function in various neurodegenerative
diseases like Alzheimer's, Huntington's, Parkinson's, and multiple sclerosis. Hesperidin, a …

[HTML][HTML] Molecular mechanisms underlying methotrexate-induced intestinal injury and protective strategies

GF Ali, EHM Hassanein, WR Mohamed - … -Schmiedeberg's Archives of …, 2024 - Springer
Methotrexate (MTX) is a folic acid reductase inhibitor that manages various malignancies as
well as immune-mediated inflammatory chronic diseases. Despite being frequently …

Hormetic effects of bioactive compounds from foods, beverages, and food dressing: the potential role in spinal cord injury

AL Fedullo, M Ciccotti, P Giannotta… - Oxidative Medicine …, 2021 - Wiley Online Library
Spinal cord injury (SCI) is a damage or trauma to the spinal cord resulting in a total or partial
loss of motor and sensory function. SCI is characterized by a disequilibrium between the …

The effectiveness of hesperidin on bisphenol A-induced spinal cord toxicity in a diabetic rat model

A Yahyazadeh - Toxicon, 2024 - Elsevier
The potential health risks of bisphenol A (BS) and diabetes (DI) has sparked public concern
due to be ubiquitous worldwide. The purpose of this study was to investigate the detrimental …

Hesperidin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology

T Donia, NM Dabbour, SA Loutfy - Handbook of Dietary Flavonoids, 2023 - Springer
The dietary flavonoid hesperidin is the most vital phytochemical in orange peel and other
citrus species and is of great general interest due to their diverse bioactivity. Very little …