Health‐related quality of life is a patient‐reported outcome that complements clinical
evaluation and provides information about disease activity and effects of the treatment. The …

OBJECTIVE: To explore if patient characteristics (pre-existing comorbidity, age, sex, and
illness severity) modify the effect of physical rehabilitation (intervention vs control) for the …

Importance Diacetylmorphine hydrochloride (the active ingredient in heroin), delivered
under supervision, is effective for the treatment of severe opioid use disorder. However …

Importance Functional impairment and pain are common indications for the initiation of
lumbar spine surgery, but information about expected improvement in these patient-reported …

Background Despite a well-established literature on the protective effect of education on
health, less is known about group differences in the mechanisms underlying this …

Study objective Nonsteroidal anti-inflammatory drugs are used extensively for the
management of acute and chronic pain, with ketorolac tromethamine being one of the most …

Aim To determine sequences and magnitude of causality among periodontitis, diabetes and
chronic kidney disease (CKD) by mediation analysis. Methods Ten‐year‐data were …

Background The long-term effects of radical resection on quality of life may influence the
treatment selection. The objective of this study was to determine whether abdominoperineal …

Background Lung cancer is associated with poor health-related quality of life (HRQoL) and
high symptom burden. This trial aimed to assess the efficacy of home-based rehabilitation …

Background Patients who survive critical illness suffer from a significant physical disability.
The impact of rehabilitation strategies on health-related quality of life is inconsistent, with …