Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational research
MR Grovola, C von Reyn, DJ Loane… - Journal of …, 2023 - Springer
Traumatic brain injury (TBI) often results in prolonged or permanent brain dysfunction with
over 2.8 million affected annually in the US, including over 56,000 deaths, with over 5 million …
over 2.8 million affected annually in the US, including over 56,000 deaths, with over 5 million …
Targets of neuroprotection and review of pharmacological interventions in traumatic brain injury
MI Hiskens - Journal of Pharmacology and Experimental …, 2022 - ASPET
Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …
manifests in cognitive, behavioral, and motor impairment. Although there have been …
Repetitive mild traumatic brain injury-induced neurodegeneration and inflammation is attenuated by acetyl-L-carnitine in a preclinical model
MI Hiskens, KM Li, AG Schneiders… - Frontiers in …, 2023 - frontiersin.org
Repetitive mild traumatic brain injuries (rmTBI) may contribute to the development of
neurodegenerative diseases through secondary injury pathways. Acetyl-L-carnitine (ALC) …
neurodegenerative diseases through secondary injury pathways. Acetyl-L-carnitine (ALC) …
Loss of consciousness and righting reflex following traumatic brain injury: predictors of post-injury symptom development (a narrative review)
Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …
Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point
Traumatic brain injury (TBI) is a major cause of disability and death. Mild TBI (mTBI)
constitutes~ 75% of all TBI cases. Repeated exposure to mTBI (rmTBI), leads to the …
constitutes~ 75% of all TBI cases. Repeated exposure to mTBI (rmTBI), leads to the …
Cognitive impairment in Chinese traumatic brain injury patients: from challenge to future perspectives
T Liu, S Yu, M Liu, Z Zhao, J Yuan, Z Sha… - Frontiers in …, 2024 - frontiersin.org
Traumatic Brain Injury (TBI) is a prevalent form of neurological damage that may induce
varying degrees of cognitive dysfunction in patients, consequently impacting their quality of …
varying degrees of cognitive dysfunction in patients, consequently impacting their quality of …
Unraveling the toxic effects mediated by the neurodegenerative disease–associated S375G mutation of TDP-43 and its S375E phosphomimetic variant
F Paron, S Barattucci, S Cappelli, M Romano… - Journal of Biological …, 2022 - ASBMB
TAR DNA-binding protein 43 (TDP-43) is a nucleic acid–binding protein found in the
nucleus that accumulates in the cytoplasm under pathological conditions, leading to …
nucleus that accumulates in the cytoplasm under pathological conditions, leading to …
Partial depletion of microglia attenuates long-term potentiation deficits following repeated blast traumatic brain injury in organotypic hippocampal slice cultures
N Varghese, B Morrison III - Journal of Neurotrauma, 2023 - liebertpub.com
Blast-induced traumatic brain injury (bTBI) has been a health concern in both military and
civilian populations due to recent military and geopolitical conflicts. Military service members …
civilian populations due to recent military and geopolitical conflicts. Military service members …
Regulation of microglial responses after pediatric traumatic brain injury: exploring the role of SHIP-1
Introduction Severe traumatic brain injury (TBI) is the world's leading cause of permanent
neurological disability in children. TBI-induced neurological deficits may be driven by …
neurological disability in children. TBI-induced neurological deficits may be driven by …
Neuroprotective Effect of Sub-lethal Hyperthermia Preconditioning in a Rat Model of Repeated Closed Head Injury
J Xiong, Y Lv, X Ma, G Peng, C Wu, J Hou, Y Zhang… - Neuroscience, 2023 - Elsevier
Repeated mild traumatic brain injury (rTBI), one of the most common forms of traumatic brain
injury, is a worldwide severe public health concern. rTBI induces cumulative neuronal injury …
injury, is a worldwide severe public health concern. rTBI induces cumulative neuronal injury …