This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

The kinetic attributes of the afferent arteriole myogenic response were investigated using the
in vitro perfused hydronephrotic rat kidney. Equations describing the time course for …

There are seven sub-families of Kir channels (Table 1), many of which have several
members. The sub-families are denoted Kit1. 0 to Kit7. 0 in the nomenclature introduced by …

The renal medullary microcirculation is a distinctive arrangement of blood vessels that serve
multiple functions in the renal medulla. This article begins with a description of the unique …

Significance: Potassium channels regulate the influx and efflux of K+ ions in various cell
types that generate and propagate action potential associated with excitation, contraction …

The control of renal vascular tone is important for the regulation of salt and water balance,
blood pressure and the protection against damaging elevated glomerular pressure. The K+ …

The transmission of elevated blood pressure to the glomerulus and pressure‐induced
glomerular injury play central roles in the pathogenesis of kidney disease and its …