Transmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles
A transmembrane (TMEM) protein with an unknown function is a type of membrane-
spanning protein expressed in the plasma membrane or the membranes of intracellular …
spanning protein expressed in the plasma membrane or the membranes of intracellular …
[HTML][HTML] The TMEM16A channel as a potential therapeutic target in vascular disease
R Al-Hosni, R Kaye, CS Choi… - Current Opinion in …, 2024 - journals.lww.com
The TMEM16A channel regulates vascular function by controlling artery tone and capillary
diameter as well as vessel formation and histology. Preclinical and clinical investigations are …
diameter as well as vessel formation and histology. Preclinical and clinical investigations are …
Wide-ranging cellular functions of ion channels and lipid scramblases in the structurally related TMC, TMEM16 and TMEM63 families
LY Jan, YN Jan - Nature Structural & Molecular Biology, 2024 - nature.com
Abstract Calcium (Ca2+)-activated ion channels and lipid scramblases in the
transmembrane protein 16 (TMEM16) family are structurally related to mechanosensitive ion …
transmembrane protein 16 (TMEM16) family are structurally related to mechanosensitive ion …
The role of anoctamin 1 in liver disease
X Li, Y Wang, L Zhang, S Yao, Q Liu… - Journal of Cellular …, 2024 - Wiley Online Library
Liver diseases include all types of viral hepatitis, alcoholic liver disease (ALD), nonalcoholic
fatty liver disease (NAFLD), cirrhosis, liver failure (LF) and hepatocellular carcinoma (HCC) …
fatty liver disease (NAFLD), cirrhosis, liver failure (LF) and hepatocellular carcinoma (HCC) …
[HTML][HTML] Low-Chloride Diet Prevents the Development of Arterial Hypertension and Protects Kidney Function in Angiotensin II-Infused Mice
J Liberona, P Araos, M Rodríguez, P León… - Kidney and Blood …, 2024 - karger.com
Introduction: A comprehensive pathophysiological mechanism to explain the relationship
between high-salt intake and hypertension remains undefined. Evidence suggests that …
between high-salt intake and hypertension remains undefined. Evidence suggests that …
Screening and identification of key biomarkers associated with endometriosis using bioinformatics and next-generation sequencing data analysis
B Vastrad, C Vastrad - Egyptian Journal of Medical Human Genetics, 2024 - Springer
Background Endometriosis is a common cause of endometrial-type mucosa outside the
uterine cavity with symptoms such as painful periods, chronic pelvic pain, pain with …
uterine cavity with symptoms such as painful periods, chronic pelvic pain, pain with …
尼氟灭酸抑制跨膜蛋白16A 参与高肺血流量诱导的肺动脉高压的机制研究
陈若霞， 潘宣任， 苏丹艳， 庞玉生 - 广西医科大学学报, 2024 - journal.gxmu.edu.cn
目的: 探讨钙激活的氯离子通道(CaCCs) 抑制剂尼氟灭酸(NFA) 和跨膜蛋白16A (TMEM16A)
在高肺血流量诱导的肺动脉高压(PAH) 中的作用及机制. 方法: 将40 只SD 大鼠随机分为normal …
在高肺血流量诱导的肺动脉高压(PAH) 中的作用及机制. 方法: 将40 只SD 大鼠随机分为normal …