The neurochemistry of autism

R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …

Executive function in autism spectrum disorder: history, theoretical models, empirical findings, and potential as an endophenotype

EA Demetriou, MM DeMayo, AJ Guastella - Frontiers in psychiatry, 2019 - frontiersin.org
This review presents an outline of executive function (EF) and its application to autism
spectrum disorder (ASD). The development of the EF construct, theoretical models of EF …

Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder

N Eissa, M Al-Houqani, A Sadeq, SK Ojha… - Frontiers in …, 2018 - frontiersin.org
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

Creativity and ADHD: A review of behavioral studies, the effect of psychostimulants and neural underpinnings

M Hoogman, M Stolte, M Baas… - … & Biobehavioral Reviews, 2020 - Elsevier
Attention deficit/hyperactivity disorder (ADHD) is a debilitating disorder and most research
therefore focuses on its deficits and its treatment. Research on the potential positive sides of …

Neuron-glia interactions in neurodevelopmental disorders

YS Kim, J Choi, BE Yoon - Cells, 2020 - mdpi.com
Recent studies have revealed synaptic dysfunction to be a hallmark of various psychiatric
diseases, and that glial cells participate in synapse formation, development, and plasticity …

Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

S Trakoshis, P Martínez-Cañada, F Rocchi, C Canella… - elife, 2020 - elifesciences.org
Excitation-inhibition (E: I) imbalance is theorized as an important pathophysiological
mechanism in autism. Autism affects males more frequently than females and sex-related …

Retinal electrophysiology in central nervous system disorders. A review of human and mouse studies

PA Constable, JKH Lim, DA Thompson - Frontiers in Neuroscience, 2023 - frontiersin.org
The retina and brain share similar neurochemistry and neurodevelopmental origins, with the
retina, often viewed as a “window to the brain.” With retinal measures of structure and …

An atlas of transcriptionally defined cell populations in the rat ventral tegmental area

RA Phillips, JJ Tuscher, SL Black, E Andraka… - Cell reports, 2022 - cell.com
The ventral tegmental area (VTA) is a complex brain region that is essential for reward
function and frequently implicated in neuropsychiatric disease. While decades of research …

Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders

P Chakraborty, A Dey, AV Gopalakrishnan… - Ageing Research …, 2023 - Elsevier
In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …

Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?

N Eissa, A Sadeq, A Sasse, B Sadek - Frontiers in pharmacology, 2020 - frontiersin.org
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …