Strategies of positron emission tomography (PET) tracer development for imaging of tau and α-synuclein in neurodegenerative disorders
S Mekala, Y Wu, YM Li - RSC Medicinal Chemistry, 2024 - pubs.rsc.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder, characterized by the
presence of extracellular amyloid plaques consisting of β-amyloid peptides (Aβ) and …
presence of extracellular amyloid plaques consisting of β-amyloid peptides (Aβ) and …
Development of Pyridothiophene Compounds for PET Imaging of α‐Synuclein
A Pees, J Tong, S Birudaraju, YS Munot… - … A European Journal, 2024 - Wiley Online Library
Aggregated α‐synuclein (α‐syn) protein is a pathological hallmark of Parkinson's disease
(PD) and Lewy body dementia (LBD). Development of positron emission tomography (PET) …
(PD) and Lewy body dementia (LBD). Development of positron emission tomography (PET) …
[HTML][HTML] 新型α 突触核蛋白PET 探针的合成及初步生物学评价
王策， 潘栋辉， 谭思怡， 王立振， 王辛宇… - NUCLEAR …, 2024 - opticsjournal.net
摘要异常聚集的α-突触核蛋白(α-synuclein) 是帕金森病的主要病理特征, 研发α-synuclein PET
显像剂有助于帕金森病的早期诊断和治疗. 本文设计并合成了一种新型α-synuclein 探针18 F …
显像剂有助于帕金森病的早期诊断和治疗. 本文设计并合成了一种新型α-synuclein 探针18 F …
Design and development of potential α-synuclein PET tracers: synthesis and evaluation of diarylpyrazole-and 2-styrylbenzothiazole-based libraries
A Di Nanni - 2024 - tobias-lib.ub.uni-tuebingen.de
Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies
(DLB) are collectively identified as synucleinopathies, a group of neurodegenerative …
(DLB) are collectively identified as synucleinopathies, a group of neurodegenerative …
Lewy body dementia
JE Galvin - CONTINUUM: Lifelong Learning in Neurology, 2024 - journals.lww.com
OBJECTIVE Lewy body dementia (LBD) is an umbrella term describing two closely related
conditions: Parkinson disease dementia (PDD) and dementia with Lewy bodies (DLB). LBD …
conditions: Parkinson disease dementia (PDD) and dementia with Lewy bodies (DLB). LBD …