Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

Physiological studies have long documented the key role played by the autonomic nervous
system in modulating cardiovascular functions and in controlling blood pressure values …

Aim The aim of this study was to determine long-term results of renal artery denervation for
treatment of treatment-resistant hypertension in the SYMPLICITY HTN-2 study. Methods …

An ablation catheter comprises a catheter body extending longitudinally between a proximal
end and a distal end along a longitudinal axis; and an ablation element assembly …

We aimed to investigate for the first time the blood pressure (BP)–lowering effect of renal
sympathetic denervation (RDN) versus clinically adjusted drug treatment in true treatment …

212 Circulation Research July 7, 2014 and others19, 20 confirmed and re-enforced these
observations. Furthermore, Osborn et al21 demonstrated that low-frequency stimulation of …

An ablation apparatus comprises an ultrasonic transducer which includes a piezoelectric
element having a cylindrical shape; a plurality of external electrodes disposed on the outer …

A catheter apparatus for assessing denervation comprises: an elongated catheter body; a
deployable structure coupled to the catheter body, the deployable structure being …

Hypertension is the most common chronic disease and the leading risk factor for disability
and premature deaths in the world, accounting for more than 9 million deaths annually …

Blood pressure (BP) response to renal denervation (RDN) is highly variable and its
effectiveness debated. A procedural end point for RDN may improve consistency of …