Since 1985, the thiazolidinedione pioglitazone has been widely used as an insulin
sensitizer drug for type 2 diabetes mellitus (T2DM). Although fluid retention was early …

The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …

The resolution of inflammation is an active and dynamic process, mediated in large part by
the innate immune system. Resolution represents not only an increase in anti‐inflammatory …

The peroxisome proliferator activated receptor γ (PPARγ) is a nuclear receptor highly
expressed in the colon and playing a key role in bacterial induced inflammation. Regulation …

CNS border-associated macrophages (BAMs) are a small population of specialised
macrophages localised in the choroid plexus, meningeal and perivascular spaces. Until …

This study evaluated whether arginine (Arg) supplementation could attenuate gut injury
induced by Escherichia coli lipopolysaccharide (LPS) challenge through an anti …

Tissue damage resulting from chemical, mechanical, and biological injury, or from
interrupted blood flow and reperfusion, is often life threatening. The subsequent tissue …

Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone
receptor superfamily of ligand-activated transcription factors that are related to retinoid …

Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a ligand-activated transcription
factor belonging to the nuclear hormone receptor superfamily. PPAR-γ regulates gene …