[HTML][HTML] Circulating biomarkers for early detection and clinical management of colorectal cancer

M Marcuello, V Vymetalkova, RPL Neves… - Molecular Aspects of …, 2019 - Elsevier
New non-invasive approaches that can complement and improve on current strategies for
colorectal cancer (CRC) screening and management are urgently needed. A growing …

DNA methylation-based testing in liquid biopsies as detection and prognostic biomarkers for the four major cancer types

V Constâncio, SP Nunes, R Henrique, C Jerónimo - Cells, 2020 - mdpi.com
Lung, breast, colorectal, and prostate cancers are the most incident worldwide. Optimal
population-based cancer screening methods remain an unmet need, since cancer detection …

[HTML][HTML] Biomarkers for detecting colorectal cancer non-invasively: DNA, RNA or proteins?

A Loktionov - World journal of gastrointestinal oncology, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a global problem affecting millions of people worldwide. This
disease is unique because of its slow progress that makes it preventable and often curable …

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)

C Rolfo, AF Cardona, M Cristofanilli, L Paz-Ares… - Critical Reviews in …, 2020 - Elsevier
Precision medicine was born with the development of new diagnostic techniques and
targeted drugs, yielding better outcomes in cancer care. With the evolution and increasing …

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine

N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA

YD Han, TJ Oh, TH Chung, HW Jang, YN Kim, S An… - Clinical …, 2019 - Springer
Background Colorectal cancer (CRC) screening can effectively reduce disease-related
mortality by detecting CRC at earlier stages. We have previously demonstrated that the …

[HTML][HTML] Current advances in detecting genetic and epigenetic biomarkers of colorectal cancer

MS Islam, V Gopalan, AK Lam, MJA Shiddiky - Biosensors and …, 2023 - Elsevier
Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, extracellular …

When tissue is an issue the liquid biopsy is nonissue: a review

J Rodríguez, J Avila, C Rolfo, A Ruíz-Patiño… - Oncology and …, 2021 - Springer
Precision medicine has impacted the field of medical oncology by introducing personalized
therapies, improving all measurable outcomes. This field, in turn, has expanded to obtaining …

Towards novel non-invasive colorectal cancer screening methods: a comprehensive review

A Ferrari, I Neefs, S Hoeck, M Peeters, G Van Hal - Cancers, 2021 - mdpi.com
Simple Summary Since the 70s, a variety of colorectal cancer (CRC) screening programs
have been adopted throughout the world with the aim of reducing the mortality rate of one of …

Multi-dimensional fragmentomic assay for ultrasensitive early detection of colorectal advanced adenoma and adenocarcinoma

X Ma, Y Chen, W Tang, H Bao, S Mo, R Liu… - Journal of hematology & …, 2021 - Springer
Previous studies on liquid biopsy-based early detection of advanced colorectal adenoma
(advCRA) or adenocarcinoma (CRC) were limited by low sensitivity. We performed a …