Opportunities and challenges in long-read sequencing data analysis
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …
broadening their application domains in genomics. Dedicated analysis tools that take into …
[HTML][HTML] Single-cell and long-read sequencing to enhance modelling of splicing and cell-fate determination
Single-cell sequencing technologies have revolutionised the life sciences and biomedical
research. Single-cell sequencing provides high-resolution data on cell heterogeneity …
research. Single-cell sequencing provides high-resolution data on cell heterogeneity …
Illuminating the dark side of the human transcriptome with long read transcript sequencing
Background The human transcriptome annotation is regarded as one of the most complete
of any eukaryotic species. However, limitations in sequencing technologies have biased the …
of any eukaryotic species. However, limitations in sequencing technologies have biased the …
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
K Sahlin, P Medvedev - Nature communications, 2021 - nature.com
Oxford Nanopore (ONT) is a leading long-read technology which has been revolutionizing
transcriptome analysis through its capacity to sequence the majority of transcripts from end …
transcriptome analysis through its capacity to sequence the majority of transcripts from end …
A technology-agnostic long-read analysis pipeline for transcriptome discovery and quantification
Alternative splicing is widely acknowledged to be a crucial regulator of gene expression and
is a key contributor to both normal developmental processes and disease states. While cost …
is a key contributor to both normal developmental processes and disease states. While cost …
tappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing
L de la Fuente, Á Arzalluz-Luque, M Tardáguila… - Genome Biology, 2020 - Springer
Recent advances in long-read sequencing solve inaccuracies in alternative transcript
identification of full-length transcripts in short-read RNA-Seq data, which encourages the …
identification of full-length transcripts in short-read RNA-Seq data, which encourages the …
De novo clustering of long-read transcriptome data using a greedy, quality value-based algorithm
K Sahlin, P Medvedev - Journal of Computational Biology, 2020 - liebertpub.com
Long-read sequencing of transcripts with Pacific Biosciences (PacBio) Iso-Seq and Oxford
Nanopore Technologies has proven to be central to the study of complex isoform …
Nanopore Technologies has proven to be central to the study of complex isoform …
[图书][B] Triatominae-The biology of chagas disease vectors
A Guarneri, M Lorenzo - 2021 - Springer
Modern systems biology has much to owe to the concept of “model species.” This label
refers to organisms that are privileged for the study of particular biological phenomena …
refers to organisms that are privileged for the study of particular biological phenomena …
Accurate spliced alignment of long RNA sequencing reads
Motivation Long-read RNA sequencing technologies are establishing themselves as the
primary techniques to detect novel isoforms, and many such analyses are dependent on …
primary techniques to detect novel isoforms, and many such analyses are dependent on …
Amplicon_sorter: A tool for reference‐free amplicon sorting based on sequence similarity and for building consensus sequences
AR Vierstraete, BP Braeckman - Ecology and Evolution, 2022 - Wiley Online Library
Abstract Oxford Nanopore Technologies (ONT) is a third‐generation sequencing technology
that is gaining popularity in ecological research for its portable and low‐cost sequencing …
that is gaining popularity in ecological research for its portable and low‐cost sequencing …