Engineered nanomedicines with enhanced tumor penetration

J Ding, J Chen, L Gao, Z Jiang, Y Zhang, M Li, Q Xiao… - Nano Today, 2019 - Elsevier
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Micro/nanoparticle‐augmented sonodynamic therapy (SDT): breaking the depth shallow of photoactivation

X Qian, Y Zheng, Y Chen - Advanced materials, 2016 - Wiley Online Library
The fast development of photoactivation for cancer treatment provides an efficient photo‐
therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal …

Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

Toward biocompatible semiconductor quantum dots: from biosynthesis and bioconjugation to biomedical application

J Zhou, Y Yang, C Zhang - Chemical reviews, 2015 - ACS Publications
The understanding of biological systems at the molecular scale is increasingly reliant on the
capability of tracking miscellaneous biomolecules and their events with improved spatial …

Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook

SM Chowdhury, L Abou-Elkacem, T Lee, J Dahl… - Journal of Controlled …, 2020 - Elsevier
Beyond the emerging field of oncological ultrasound molecular imaging, the recent
significant advancements in ultrasound and contrast agent technology have paved the way …

External triggering and triggered targeting strategies for drug delivery

Y Wang, DS Kohane - Nature Reviews Materials, 2017 - nature.com
Drug delivery systems that are externally triggered to release drugs and/or target tissues
hold considerable promise for improving the treatment of many diseases by minimizing …

Application of ensemble machine learning approach to assess the factors affecting size and polydispersity index of liposomal nanoparticles

B Hoseini, MR Jaafari, A Golabpour… - Scientific Reports, 2023 - nature.com
Liposome nanoparticles have emerged as promising drug delivery systems due to their
unique properties. Assessing particle size and polydispersity index (PDI) is critical for …

Gene therapy for drug-resistant glioblastoma via lipid-polymer hybrid nanoparticles combined with focused ultrasound

Q Yang, Y Zhou, J Chen, N Huang… - International journal of …, 2021 - Taylor & Francis
Background Therapy for glioblastoma (GBM) has always been very challenging, not only
because of the presence of the blood-brain barrier (BBB) but also due to susceptibility to …

pH-sensitive nano-systems for drug delivery in cancer therapy

J Liu, Y Huang, A Kumar, A Tan, S Jin, A Mozhi… - Biotechnology …, 2014 - Elsevier
Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …