Parkinson's disease

BR Bloem, MS Okun, C Klein - The Lancet, 2021 - thelancet.com
Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

Transcranial magnetic stimulation, deep brain stimulation, and other forms of neuromodulation for substance use disorders: Review of modalities and implications for …

JJ Mahoney III, CA Hanlon, PJ Marshalek… - Journal of the …, 2020 - Elsevier
Given the high prevalence of individuals diagnosed with substance use disorder, along with
the elevated rate of relapse following treatment initiation, investigating novel approaches …

Focused ultrasound thalamotomy for tremor in Parkinson's disease: outcomes in a large, prospective cohort

MMJ Chua, SE Blitz, PR Ng, DJ Segar… - Movement …, 2023 - Wiley Online Library
Background Magnetic resonance guided focused ultrasound (MRgFUS) is United States
Food and Drug Administration approved for the treatment of tremor‐dominant Parkinson's …

The role of high‐intensity focused ultrasound as a symptomatic treatment for Parkinson's disease

S Moosa, R Martínez‐Fernández, WJ Elias… - Movement …, 2019 - Wiley Online Library
MR‐guided focused ultrasound is a novel, minimally invasive surgical procedure for
symptomatic treatment of PD. With this technology, the ventral intermediate nucleus, STN …

Focused ultrasound thalamotomy in tremor dominant Parkinson's disease: long-term results

A Sinai, M Nassar, E Sprecher… - Journal of …, 2022 - content.iospress.com
Background: MRI-guided focused ultrasound (FUS) has established short-term efficacy in
tremor relief. Objective: We report our long-term experience of treating tremor with unilateral …

Novel targeted therapies for Parkinson's disease

T Ntetsika, PE Papathoma, I Markaki - Molecular Medicine, 2021 - Springer
Parkinson's disease (PD) is the second more common neurodegenerative disease with
increasing incidence worldwide associated to the population ageing. Despite increasing …

Focused ultrasound thalamotomy for tremor-dominant Parkinson's disease: a prospective 1-year follow-up study

K Yamamoto, H Ito, S Fukutake, T Odo… - Neurologia medico …, 2021 - jstage.jst.go.jp
Transcranial magnetic resonance (MR)-guided focused ultrasound (FUS) therapy is an
emerging and minimally invasive treatment for movement disorders. There are limited …

Cognitive effects of unilateral thalamotomy for tremor: a meta-analysis

CR Rohringer, IJ Sewell, S Gandhi, J Isen… - Brain …, 2022 - academic.oup.com
Tremor is a debilitating symptom that can lead to functional impairment. Pharmacotherapy is
often successful, but up to 50% of patients are resistant to medications or cannot tolerate …

Focused ultrasound and other lesioning in the treatment of tremor

DK Binder, BB Shah, WJ Elias - Journal of the Neurological Sciences, 2022 - Elsevier
There has been a long history of lesioning procedures to treat tremor associated with both
essential tremor (ET) and Parkinson's disease (PD). These include radiofrequency (RF) …

Neuroimaging signatures predicting motor improvement to focused ultrasound subthalamotomy in Parkinson's disease

SJ Lin, R Rodriguez-Rojas, TR Baumeister… - npj Parkinson's …, 2022 - nature.com
Subthalamotomy using transcranial magnetic resonance-guided focused ultrasound
(tcMRgFUS) is a novel and promising treatment for Parkinson's Disease (PD). In this study …