The graded multidimensional geometry of phenotypic variation and progression in neurodegenerative syndromes

S Ramanan, D Akarca, SK Henderson, MA Rouse… - Brain, 2024 - academic.oup.com
Clinical variants of Alzheimer's disease and frontotemporal lobar degeneration display a
spectrum of cognitive-behavioural changes varying between individuals and over time …

Data-driven neuroanatomical subtypes of primary progressive aphasia

B Taylor, M Bocchetta, C Shand, EG Todd… - Brain, 2024 - academic.oup.com
The primary progressive aphasias are rare, language-led dementias, with three main
variants: semantic, non-fluent/agrammatic, and logopenic. Whilst semantic variant has a …

Mapping the multidimensional geometric landscape of graded phenotypic variation and progression in neurodegenerative syndromes

S Ramanan, D Akarca, SK Henderson, MA Rouse… - medRxiv, 2023 - medrxiv.org
Clinical variants of Alzheimer's disease and frontotemporal lobar degeneration display a
spectrum of cognitive-behavioural changes varying between individuals and over time …

Frontoparietal network integrity supports cognitive function despite atrophy and hypoperfusion in pre-symptomatic frontotemporal dementia: multimodal analysis of …

X Liu, PS Jones, M Pasternak, M Masellis, A Bouzigues… - medRxiv, 2024 - medrxiv.org
INTRODUCTION: Gene carriers of frontotemporal dementia can remain cognitively well
despite neurodegeneration. A better understanding of brain structural, perfusion and …

Frontoparietal network integrity supports cognitive function in pre‐symptomatic frontotemporal dementia: Multimodal analysis of brain function, structure, and perfusion

X Liu, PS Jones, M Pasternak, M Masellis… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Genetic mutation carriers of frontotemporal dementia can remain
cognitively well despite neurodegeneration. A better understanding of brain structural …