Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

There is now consistent evidence that neural oscillation at low‐and high‐frequencies
constitute an important aspect of the pathophysiology of schizophrenia. Specifically …

The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …

Excessive neural variability of sensory responses is a hallmark of atypical sensory
processing in autistic individuals with cascading effects on other core autism symptoms but …

The mechanistic underpinnings of autism remain a subject of debate and controversy. Why
do individuals with autism share an overlapping set of atypical behaviors and symptoms …

Abstract Fragile X Syndrome (FXS) is a monogenetic form of intellectual disability and
autism in which well-established knockout (KO) animal models point to neuronal …

Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability (ID)
and a primary genetic cause of autism spectrum disorder (ASD). FXS arises from the …

Schizophrenia is a heterogeneous psychiatric disorder with a strong genetic basis, whose
etiology and pathophysiology remain poorly understood. Exome sequencing studies have …

Abstract Study Objectives Idiopathic/isolated rapid eye movement-sleep behavior disorder
(iRBD) often precedes the onset of synucleinopathies. Here, we investigated whether …

Mutations in SYNGAP1, a protein enriched at glutamatergic synapses, cause intellectual
disability associated with epilepsy, autism spectrum disorder, and sensory dysfunctions …