New applications of synthetic biology tools for cyanobacterial metabolic engineering

M Santos-Merino, AK Singh, DC Ducat - Frontiers in bioengineering …, 2019 - frontiersin.org
Cyanobacteria are promising microorganisms for sustainable biotechnologies, yet unlocking
their potential requires radical re-engineering and application of cutting-edge synthetic …

Diverse light responses of cyanobacteria mediated by phytochrome superfamily photoreceptors

LB Wiltbank, DM Kehoe - Nature Reviews Microbiology, 2019 - nature.com
Cyanobacteria are an evolutionarily and ecologically important group of prokaryotes. They
exist in diverse habitats, ranging from hot springs and deserts to glaciers and the open …

CyanoGate: a modular cloning suite for engineering cyanobacteria based on the plant MoClo syntax

R Vasudevan, GAR Gale, AA Schiavon… - Plant …, 2019 - academic.oup.com
Recent advances in synthetic biology research have been underpinned by an exponential
increase in available genomic information and a proliferation of advanced DNA assembly …

Challenges and opportunity of recent genome editing and multi-omics in cyanobacteria and microalgae for biorefinery

WR Lin, SI Tan, CC Hsiang, PK Sung, IS Ng - Bioresource technology, 2019 - Elsevier
Microalgae and cyanobacteria are easy to culture, with higher growth rates and
photosynthetic efficiencies compared to terrestrial plants, and thus generating higher …

A critical review of genome editing and synthetic biology applications in metabolic engineering of microalgae and cyanobacteria

IS Ng, BB Keskin, SI Tan - Biotechnology Journal, 2020 - Wiley Online Library
Being the green gold of the future, microalgae and cyanobacteria have recently attracted
considerable interest worldwide, for their metabolites such as lipids, protein, pigments, and …

Toolboxes for cyanobacteria: recent advances and future direction

T Sun, S Li, X Song, J Diao, L Chen, W Zhang - Biotechnology advances, 2018 - Elsevier
Photosynthetic cyanobacteria are important primary producers and model organisms for
studying photosynthesis and elements cycling on earth. Due to the ability to absorb sunlight …

CRISPRi-dCas12a: a dCas12a-mediated CRISPR interference for repression of multiple genes and metabolic engineering in cyanobacteria

SY Choi, HM Woo - ACS synthetic biology, 2020 - ACS Publications
In cyanobacteria, metabolic engineering using synthetic biology tools is limited to build a
biosolar cell factory that converts CO2 to value-added chemicals, as repression of essential …

Progress and challenges in engineering cyanobacteria as chassis for light‐driven biotechnology

A Hitchcock, CN Hunter, DP Canniffe - Microbial biotechnology, 2020 - Wiley Online Library
Cyanobacteria are prokaryotic phototrophs that, in addition to being excellent model
organisms for studying photosynthesis, have tremendous potential for light‐driven synthetic …

Recent advances in synthetic biology of cyanobacteria

A Sengupta, HB Pakrasi, PP Wangikar - Applied microbiology and …, 2018 - Springer
Cyanobacteria are attractive hosts that can be engineered for the photosynthetic production
of fuels, fine chemicals, and proteins from CO 2. Moreover, the responsiveness of these …

Light and carbon: Synthetic biology toward new cyanobacteria-based living biomaterials

IM Goodchild-Michelman, GM Church, MG Schubert… - Materials Today Bio, 2023 - Elsevier
Cyanobacteria are ideal candidates to use in developing carbon neutral and carbon
negative technologies; they are efficient photosynthesizers and amenable to genetic …