Pluronics are triblock (PEO ab-PPO bb-PEO a) copolymers, commercially available in a
range of amphiphilicity. Usually, pluronics self-assemble in aqueous solution to form core …

Multiple myeloma (MM) is an incurable malignancy of clonal plasma cells, characterized by
high relapse rates and rapid development of drug resistance. The emergence of proteasome …

Quercetin (QCN) is a plant polyphenol with a variety of medicinal effects. Poor water
solubility, on the other hand, restricts its therapeutic effectiveness. The purpose of this study …

Multidrug resistance (MDR) seriously hinders therapeutic efficacy in clinical cancer
treatment. Herein, we reported new polymeric prodrug micelles with tumor-targeting and …

Multidrug resistance (MDR) is one of the major obstacles to clinical cancer chemotherapy.
Herein, we designed new pH-sensitive pluronic micelles with the synergistic effects of …

The anti-diabetic glipizide (GLN) drug has notable pharmaceutical advantages, but poor
aqueous solubility restricts its wide applications. The present work was to develop a mixed …

In the pharmaceutical formulation of anticancer drugs, US FDA-approved cyclodextrin (CD)
and its derivates have been widely employed. Among them, hydroxypropyl β-cyclodextrin …

Efficient targeting to tumor tissues and subsequent rapid drug release in cancer cells
remains a major challenge for nanodrug delivery systems. Herein, smart nanodrug particles …

Abstract Resveratrol (Res), a non-flavonoid polyphenolic compound extracted from natural
plants, has many pharmacological effects such as anti-tumor, organ protection, improvement …