Microbial communities perform metabolic processes that sustain life on Earth and promote
human health. Microbial consortia sustain these functions in the face of constant structural …

This paper addresses two topics in systems biology, the hypothesis that biological systems
are modular and the problem of relating structure and function of biological systems. The …

Fluctuations in the anaerobic digestion (AD) organic loading rate (OLR) cause shocks to the
AD microbiome, which lead to unstable methane productivity. Managing these fluctuations …

Understanding the origins and impacts of novel traits has been a perennial interest in many
realms of ecology and evolutionary biology. Here, we build on previous evolutionary and …

The existence of an environmentally regulated version of meiotic crossing-over, or eco-
crossover, is proposed, and the main consequences of this hypothesis are considered. Eco …

The role of mutations have been subject to many controversies since the formation of the
Modern Synthesis of evolution in the early 1940ties. Geneticists in the early half of the …

How living systems achieve precision in form and function despite their intrinsic stochasticity
is a fundamental yet ongoing question in biology. We generated morphomaps of …

This paper presents the foundation for a decomposition theory for Boolean networks, a type
of discrete dynamical system that has found a wide range of applications in the life sciences …

Much of the striking diversity of life on Earth has arisen from variations in the way that the
same molecules and networks operate during development to shape and pattern tissues …

Simple models, in which genetic robustness is expressed as the probability that a mutation
is neutral, appear to offer disparate views of the relationship between robustness and …