Programmed cell death (PCD) pathways, including apoptosis and regulated necrosis, are
required for normal cell turnover and tissue homeostasis. Mis-regulation of PCD is …

Saccharomyces cerevisiae has directly or indirectly contributed to the identification of
arguably more mammalian genes that affect aging than any other model organism. Aging in …

Ageing results from complex genetically and epigenetically programmed processes that are
elicited in part by noxious or stressful events that cause programmed cell death. Here, we …

The phenomenon of aging is an intrinsic feature of life. Accordingly, the possibility to
manipulate it has fascinated humans likely since time immemorial. Recent evidence is …

One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death
(called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and …

Autophagy protects organelles, cells, and organisms against several stress conditions.
Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide …

Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …

A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …

Yeasts, such as Saccharomyces cerevisiae, have long served as useful models for the study
of oxidative stress, an event associated with cell death and severe human pathologies. This …