Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …

Ferroptosis, a novel form of regulated cell death induced by iron-dependent lipid
peroxidation, plays an essential role in the development and drug resistance of tumors …

Background Non-small cell lung cancer (NSCLC) is the most common type of human lung
cancers, which has diverse pathological features. Although many signaling pathways and …

The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

Lung cancer remains a formidable global health burden, necessitating a comprehensive
understanding of the underlying molecular mechanisms driving its progression. Recently …

Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …

Neuroinflammation plays a crucial role in the secondary phase of spinal cord injury (SCI),
and is initiated following the activation of toll-like receptor 4 (TLR4). However, the …

Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Cancer is a disease characterized by uncontrolled cell proliferation, but the precise
pathological mechanisms underlying tumorigenesis often remain to be elucidated. In recent …