Preventive and therapeutic use of herbal compounds against doxorubicin induced hepatotoxicity: a comprehensive review

F Mahmoudi, O Arasteh, S Elyasi - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
Doxorubicin (DOX) is associated with numerous acute and chronic dose-related toxicities
including hepatotoxicity. This adverse reaction may limit the use of other chemotherapeutic …

Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis

G Oktem, A Uysal, O Oral, ED Sezer, M Olukman… - Experimental and …, 2012 - Elsevier
Although doxorubicin (DOX) is a commonly used chemotherapeutic agent its clinical use is
restricted due to its organ toxicities. The present investigation relates to reducing DOX …

[PDF][PDF] Protective effects of ruitn and/or hesperidin against doxorubicin-induced hepatotoxicity

WG Hozayen, HS Abou Seif, S Amin - Int J Clin Nutr, 2014 - academia.edu
The present study was conducted to evaluate the protective role of rutin and hesperidin on
experimental doxorubicin induced hepatotoxicity. Doxorubicin (DXR) administered rats (25 …

[HTML][HTML] Protective efficacy of alpha-lipoic acid against aflatoxinB1-induced oxidative damage in the liver

Y Li, QG Ma, LH Zhao, YQ Guo, GX Duan… - … journal of animal …, 2014 - ncbi.nlm.nih.gov
Alpha-lipoic acid (α-LA) is not only involved in energy metabolism, but is also a powerful
antioxidant that can protect against hepatic oxidative stress induced by some drugs, toxins …

[HTML][HTML] Effects of standardized Zataria multiflora extract and its major ingredient, Carvacrol, on Adriamycin-induced hepatotoxicity in rat

R Mohebbati, M Paseban, M Soukhtanloo, M Jalili-Nik… - Biomedical journal, 2018 - Elsevier
Background At a glance commentary Scientific background on the subject Since Adriamycin
is used as an anticancer drug among various communities and is one of its side-effects, it is …

Cardioprotective and hepatoprotective effects of Citrus hystrix peels extract on rats model

H Putri, S Nagadi, YA Larasati, N Wulandari… - Asian Pacific journal of …, 2013 - Elsevier
Objective To observe the combination effect of doxorubicin and Citrus hystrix (kaffir lime's)
peel ethanolic extract (ChEE) on blood serum alanine aminotransferase (ALT) and aspartate …

[HTML][HTML] p-Coumaric acid alleviates adriamycin-induced hepatotoxicity in rats

Z Rafiee, MZ Moaiedi, AV Gorji… - Asian Pacific Journal of …, 2021 - journals.lww.com
Objective: To evaluate the effect of p-coumaric acid against adriamycin-induced
hepatotoxicity in rats. Methods: The rats were divided into 4 groups. The control group …

None Herbal Agents as Preventive and Therapeutic Measures for Doxorubicin Induced Hepatotoxicity: A Comprehensive Review

F Mahmoudi, S Elyasi - Journal of Pharmaceutical Care, 2022 - jpc.tums.ac.ir
Cancer is one of the most common human diseases and a leading cause of human mortality
in rencent years. Doxorubicin (DOX) is an important anti-cancer agent belonging to …

Evaluation of the University of Florida lomustine, vincristine, procarbazine, and prednisone chemotherapy protocol for the treatment of relapsed lymphoma in dogs: 33 …

CE Fahey, RJ Milner, K Barabas, D Lurie… - Journal of the …, 2011 - Am Vet Med Assoc
Objective—To evaluate the toxicity and efficacy of a modification of a previously evaluated
combination of lomustine, vincristine, procarbazine, and prednisone (LOPP) as a rescue …

Ameliorating oxidative stress and inflammation by Hesperidin and vitamin E in doxorubicin induced cardiomyopathy

T Donia, S Eldaly, EMM Ali - Turkish Journal of Biochemistry, 2019 - degruyter.com
Background Doxorubicin (DOX) is a common chemotherapeutic drug. However, it causes
cardiomyopathy which reduces its clinical use in human cancer therapy. Objective The …