Targeting apoptosis and autophagy following spinal cord injury: Therapeutic approaches to polyphenols and candidate phytochemicals
Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …
motor function. Understanding the precise dysregulated signaling pathways, especially …
The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection
AR Khalatbary, E Khademi - Nutritional neuroscience, 2020 - Taylor & Francis
Epigallocatechin gallate is the most abundant composition of the tea catechins and is
thought to be responsible for the majority of biological activity of green tea extracts such as …
thought to be responsible for the majority of biological activity of green tea extracts such as …
Mechanisms underlying the effects of the green tea polyphenol EGCG in sarcopenia prevention and management
T Wang, H Xu, S Wu, Y Guo, G Zhao… - Journal of Agricultural …, 2023 - ACS Publications
Sarcopenia is prevalent among the older population and severely affects human health. Tea
catechins may benefit for skeletal muscle performance and protect against secondary …
catechins may benefit for skeletal muscle performance and protect against secondary …
The importance of natural antioxidants in the treatment of spinal cord injury in animal models: an overview
A Coyoy-Salgado, JJ Segura-Uribe… - Oxidative Medicine …, 2019 - Wiley Online Library
Patients with spinal cord injury (SCI) face devastating health, social, and financial
consequences, as well as their families and caregivers. Reducing the levels of reactive …
consequences, as well as their families and caregivers. Reducing the levels of reactive …
Ultramicronized palmitoylethanolamide and paracetamol, a new association to relieve hyperalgesia and pain in a sciatic nerve injury model in rat
Inflammation is known to be an essential trigger of the pathological changes that have a
critical impact on nerve repair and regeneration; moreover, damage to peripheral nerves …
critical impact on nerve repair and regeneration; moreover, damage to peripheral nerves …
Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush
Background Animal models of sciatic nerve injury are commonly used to study neuropathic
pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion …
pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion …
Catechins enhance skeletal muscle performance
P Li, A Liu, W Xiong, H Lin, W Xiao… - Critical reviews in …, 2020 - Taylor & Francis
Muscle-related disorders, such as sarcopenia and cachexia, caused by aging and chronic
diseases can lead to the loss of muscle mass and strength to different degrees, severely …
diseases can lead to the loss of muscle mass and strength to different degrees, severely …
[HTML][HTML] A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines
LM Urdzikova, J Ruzicka, K Karova, A Kloudova… - …, 2017 - Elsevier
Spinal cord injury (SCI) is a debilitating condition which is characterized by an extended
secondary injury due to the presence of inflammatory local milieu. Epigallocatechin gallate …
secondary injury due to the presence of inflammatory local milieu. Epigallocatechin gallate …
[HTML][HTML] NGF and PI3K/Akt signaling participate in the ventral motor neuronal protection of curcumin in sciatic nerve injury rat models
Q Sang, D Sun, Z Chen, W Zhao - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objective It has been reported that sciatic nerve injury (SNI) leads to degeneration, damage,
and apoptosis of motor neurons. Nerve growth factor (NGF) plays a pivotal role in …
and apoptosis of motor neurons. Nerve growth factor (NGF) plays a pivotal role in …
Epigallocatechin gallate modulates essential elements, Zn/Cu ratio, hazardous metal, lipid peroxidation, and antioxidant activity in the brain cortex during cerebral …
MC Lin, CC Liu, YC Lin, CW Hsu - Antioxidants, 2022 - mdpi.com
Cerebral ischemia induces oxidative brain injury via increased oxidative stress.
Epigallocatechin gallate (EGCG) exerts anti-oxidant, anti-inflammatory, and metal chelation …
Epigallocatechin gallate (EGCG) exerts anti-oxidant, anti-inflammatory, and metal chelation …