[HTML][HTML] Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

L Wang, Y Yan, L Wu, J Peng - Pharmacological Research, 2023 - Elsevier
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most
prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and …

[HTML][HTML] Multifaceted effects of obesity on cancer immunotherapies: bridging preclinical models and clinical data

LV Vick, RJ Canter, AM Monjazeb… - Seminars in cancer biology, 2023 - Elsevier
Obesity, defined by excessive body fat, is a highly complex condition affecting numerous
physiological processes, such as metabolism, proliferation, and cellular homeostasis. These …

Prebiotics progress shifts in the intestinal microbiome that benefits patients with type 2 diabetes mellitus

L Vitetta, NN Gorgani, G Vitetta, JD Henson - Biomolecules, 2023 - mdpi.com
Hypoglycemic medications that could be co-administered with prebiotics and functional
foods can potentially reduce the burden of metabolic diseases such as Type 2 Diabetes …

TFAM-mediated intercellular lipid droplet transfer promotes cadmium-induced mice nonalcoholic fatty liver disease

J Sun, L Yan, Y Chen, T Wang, W Ali, Y Ma… - Journal of Hazardous …, 2024 - Elsevier
Abstracts Cadmium (Cd) is an important environmental pollutant. Herein, we discovered a
new way of lipid accumulation, where lipid droplets can be transferred across cells. In this …

[HTML][HTML] The Impact of Gastrointestinal Hormones on Human Adipose Tissue Function

M Radziszewska, L Ostrowska… - Nutrients, 2024 - pmc.ncbi.nlm.nih.gov
Background: Obesity is a global issue, the development of which depends on many
interacting factors. Among these, hormones secreted in the gastrointestinal tract play an …

Association between triglyceride to high-density lipoprotein cholesterol ratio and nonalcoholic fatty liver disease and liver fibrosis in American adults: an observational …

J Wang, H Li, X Wang, R Shi, J Hu, X Zeng… - Frontiers in …, 2024 - frontiersin.org
Objective This study investigated the link between triglyceride to high-density lipoprotein
cholesterol (TG/HDL-C) ratio and nonalcoholic fatty liver disease (NAFLD) and liver fibrosis …

[HTML][HTML] Comparative Effects of Gymnema sylvestre and Berberine on Adipokines, Body Composition, and Metabolic Parameters in Obese Patients: A Randomized …

C Bandala, J Carro-Rodríguez, N Cárdenas-Rodríguez… - Nutrients, 2024 - mdpi.com
Gymnema sylvestre (GS) and berberine (BBR) are natural products that have demonstrated
therapeutic potential for the management of obesity and its comorbidities, as effective and …

Associations between co-exposure to per-and polyfluoroalkyl substances and metabolic diseases: The mediating roles of inflammation and oxidative stress

Z Chen, W Wei, Y Hu, Q Niu, Y Yan - Science of The Total Environment, 2024 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS) pose potential risks to human
health. In real-world settings, humans are exposed to various PFAS through numerous …

European Association for the Study of Obesity (EASO) Position Statement on medical nutrition therapy for the management of individuals with overweight or obesity …

G Muscogiuri, L Barrea, S Bettini, M El Ghoch, N Katsiki… - Obesity Facts, 2024 - karger.com
Obesity, a prevalent and multifactorial disease, is linked to a range of metabolic
abnormalities, including insulin resistance, dyslipidemia, and chronic inflammation. These …

The combined effects of high-intensity interval exercise training and dietary supplementation on reduction of body fat in adults with overweight and obesity: a …

E Gaweł, B Hall, S Siatkowski, A Grabowska… - Nutrients, 2024 - mdpi.com
Excessive body fat is associated with various comorbidities including cardiovascular
disease, type 2 diabetes mellitus and certain types of cancer. The search for effective …