The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O2
and CO2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to …

The carotid body (CB) is an arterial chemoreceptor organ located in the carotid bifurcation
and has a well-recognized role in cardiorespiratory regulation. The CB contains …

The relationship between obstructive sleep apnea (OSA) and endocrine and metabolic
disease is unequivocal. OSA, which is characterized by intermittent hypoxia and sleep …

The growing number of patients with obstructive sleep apnea is challenging healthcare
systems worldwide. Obstructive sleep apnea is characterized by chronic intermittent …

Rationale: Obesity leads to resistant hypertension and mechanisms are poorly understood,
but high plasma levels of leptin have been implicated. Leptin increases blood pressure …

Obesity hypoventilation syndrome (OHS) is defined as daytime hypercapnia in obese
individuals in the absence of other underlying causes. In the United States, OHS is present …

Key points Leptin is a potent respiratory stimulant. A long functional isoform of leptin
receptor, LepRb, was detected in the carotid body (CB), a key peripheral hypoxia sensor …

Abstract Objective The carotid bodies (CBs) are peripheral chemoreceptor organs
classically described as being O2 sensors, which are increasingly emerging as core players …

Sleep disordered breathing (SDB) is a complex, sex specific and highly heterogeneous
group of respiratory disorders. Nevertheless, sleep fragmentation and repeated fluctuations …

Carotid bodies (CBs) are peripheral chemoreceptors that sense changes in blood O2, CO2,
and pH levels. Apart from ventilatory control, these organs are deeply involved in the …