Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

This review provides an update on the current clinical and preclinical understanding of
chemotherapy induced peripheral neuropathy (CIPN). The overview of the clinical syndrome …

Animal models are pivotal for understanding the mechanism of neuropathic pain and
development of effective therapy for its optimal management. A battery of neuropathic pain …

Chemotherapy induced peripheral neuropathy (CIPN) is a type of neuropathic pain that is a
major dose-limiting side-effect of potentially curative cancer chemotherapy treatment …

Neurotoxic side effects of cancer therapy are second in frequency to hematological toxicity.
Unlike hematological side effects that can be treated with hematopoietic growth factors …

Neurotoxicity is a burdensome side effect of platinum-based chemotherapy that prevents
administration of the full efficacious dosage and often leads to treatment withdrawal …

TRPA1 is a non‐selective cation channel expressed in mammalian peripheral pain
receptors, with a major role in chemonociception. TRPA1 has also been implicated in …

Chemotherapy‐induced peripheral neuropathy (CIPN) is a serious adverse side effect of
many chemotherapeutic agents, affecting> 60% of patients with cancer. Moreover, CIPN …

Cancer chemotherapeutics like paclitaxel and oxaliplatin produce a dose-limiting chronic
sensory peripheral neuropathy that is often accompanied by neuropathic pain. The cause of …

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and painful condition
seen in patients undergoing treatment with common agents such as vincristine, paclitaxel …