[HTML][HTML] The gut-brain axis mediates bacterial driven modulation of reward signaling

JS Kim, KC Williams, RA Kirkland, R Schade… - Molecular …, 2023 - Elsevier
Objective Our goal is to investigate if microbiota composition modulates reward signaling
and assess the role of the vagus in mediating microbiota to brain communication. Methods …

[HTML][HTML] AgRP neuron activity promotes associations between sensory and nutritive signals to guide flavor preference

NT Nyema, AD McKnight, AG Vargas-Elvira… - Molecular …, 2023 - Elsevier
Objective The learned associations between sensory cues (eg, taste, smell) and nutritive
value (eg, calories, post-ingestive signaling) of foods powerfully influences our eating …

[HTML][HTML] Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake

CM Lorch, NW Hayes, JL Xia, SW Fleps, HE McMorrow… - Cell reports, 2024 - cell.com
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-
induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of …

[HTML][HTML] High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight

AC Korgan, K Oliveira-Abreu, W Wei… - International Journal of …, 2023 - nature.com
Abstract Background/Objective As the obesity epidemic continues, the understanding of
macronutrient influence on central nervous system function is critical for understanding diet …

Sucrose overconsumption impairs feeding circuit dynamics and promotes palatable food intake

CM Lorch, NW Hayes, JL Xia, SW Fleps, HE McMorrow… - bioRxiv, 2023 - biorxiv.org
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-
induced obesity through mechanisms that remain obscure. Specifically, the role of …