Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

Rapid-cycling in bipolar disorder (RC-BD) is associated with greater illness morbidity and
inferior treatment response but many aspects remain unclear, prompting this systematic …

Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …

Dysfunction in a wide array of systems—including the immune, monoaminergic, and
glutamatergic systems—is implicated in the pathophysiology of depression. One potential …

The monoamine hypothesis has dominated research on the pathophysiology of mood
disorders as well as the development of therapeutic drugs by over half a century. Nowadays …

The exact neurobiological mechanisms of bipolar disorder (BD) remain unknown. However,
some neurometabolites could be implicated, including Glutamate (Glu), Glutamine (Gln) …

Post-stroke depression (PSD) is the most frequent and important neuropsychiatric
consequence of stroke. It is strongly associated with exacerbated deterioration of functional …

Glutamate is implicated in the neuropathology of both major depressive disorder and bipolar
disorder. Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter in …

The avian optic tectum (OT) has been studied for its diverse functions, yet a comprehensive
molecular landscape at the cellular level has been lacking. In this study, we applied spatial …

Addressing the formidable challenge posed by the development of effective and
personalized interventions for major depressive disorder (MDD) necessitates a …