Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

Irinotecan hydrochloride is a camptothecin derivative that exerts antitumor activity against a
variety of tumors. SN-38 produced in the body by carboxylesterase is the active metabolite of …

Purpose To provide recommendations for appropriate cytotoxic chemotherapy dosing for
obese adult patients with cancer. Methods The American Society of Clinical Oncology …

While patient age and gender are important factors in the clinical decision‐making for
treating urothelial carcinoma of the bladder (UCB), there are no evidence‐based …

As a result of an increasing life expectancy, the incidence of cancer cases diagnosed in the
older population is rising. Indeed, cancer incidence is 11-fold higher in persons over the age …

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer
mortality in women worldwide. Elderly individuals make up a large part of the breast cancer …

Docetaxel is an effective treatment approved in five key cancers, but its effectiveness in
clinical practice can be compromised by sub-optimal side-effect management. The aim of …

Despite the sustained trend of decreasing overall cancer incidence, the number of elderly
patients with cancer will considerably increase in the coming years, as the incidence of …

Background Cancer incidence increases exponentially with advancing age, cancer patients
live longer than in the past, and many new treatments focus on stabilizing disease and …