Cytotoxicity and chemotherapeutic potential of natural rosin abietane diterpenoids and their synthetic derivatives

C Faustino, Í Neto, P Fonte… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Cancer is a major cause of morbidity and mortality worldwide. Chemotherapeutic agents
currently used in cancer treatment are associated with severe side effects and development …

Ugi multicomponent-reaction: Syntheses of cytotoxic dehydroabietylamine derivatives

J Wiemann, L Fischer, J Kessler, D Ströhl, R Csuk - Bioorganic chemistry, 2018 - Elsevier
Isocyanide-based multicomponent reactions–especially the standard four component Ugi
reaction–provide an easy and powerful access to compounds with an auspicious …

[HTML][HTML] Dehydroabietylamine-substituted trifluorobenzene sulfonamide rhodamine B hybrids as anticancer agents overcoming drug resistance

NV Heise, SJ Meyer, R Csuk, T Mueller - European Journal of Medicinal …, 2024 - Elsevier
Attachment of a conjugate assembled from a novel fluorinated carbonic anhydrase inhibitor
and rhodamine B onto dehydroabietylamine (DHA) or cyclododecylamine led to first-in-class …

Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity

J Wiemann, L Fischer, M Rohmer, R Csuk - European Journal of Medicinal …, 2018 - Elsevier
Due to their auspicious pharmacological efficacy as future drug candidates, natural products
have been attracting scientific interest for centuries. An interesting field of research concerns …

去氢枞酸固液溶解度及其反应-结晶耦合单离方法.

任宝光, 杨和见, 陈小鹏, 侯文彪… - Biomass Chemical …, 2024 - search.ebscohost.com
采用激光监视技术判断平衡终点, 由动态法测定了282~ 325 K 去氢枞酸在甲醇, 无水乙醇,
正丙醇, 正丁醇中的固液溶解度; 应用λh 模型, Wilson 模型, 简化模型分别对溶解度数据进行关联 …