Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and …

CC Onyekweli, B Ben-Azu, OM Oyovwi… - Food and Chemical …, 2024 - Elsevier
This study investigated whether epigallocatechin-gallate (EGCG) could counteract the
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …

Psychopharmacological interaction of alcohol and posttraumatic stress disorder: Effective action of naringin

B Ben-Azu, B Oritsemuelebi, AM Oghorodi… - European journal of …, 2024 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are prevalently co-
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …

[HTML][HTML] Geraniol mitigates anxiety-like behaviors in rats by reducing oxidative stress, repairing impaired hippocampal neurotransmission, and normalizing brain …

R Nisar, A Inamullah, AUF Ghalib, H Nisar… - Biomedicine & …, 2024 - Elsevier
Anxiety-like conditions can interfere with daily activities as the adaptive mechanism fails to
cope with stress. These conditions are often linked with increased oxidative stress, and …

Alcohol exacerbates psychosocial stress-induced neuropsychiatric symptoms: Attenuation by geraniol

B Ben-Azu, A Adebesin, GE Moke, VO Ojiokor… - Neurochemistry …, 2024 - Elsevier
Adaptation to psychosocial stress is psychologically distressing, initiating/promoting
comorbidity with alcohol use disorders. Emerging evidence moreover showed that ethanol …

[HTML][HTML] A study on the improvement of lipid metabolism disorders in the treatment of hyperprolactinemia rats with liver-depression by Sini San based on AKT1/TNF/IL6 …

W Xu, S Tian, G Mao, Y Li, H Qian, W Tao - Current Research in Food …, 2024 - Elsevier
Sini San (SNS) is used to treat liver depression and is applied in both food and herbal
medicine. Hyperprolactinemia (HPRL) is a common endocrine disorder, and patients with …

Carvacrol alleviates CUMS-induced depressive-like behaviors and cognitive impairment by reducing oxidative stress and neuroinflammation in mice

JT Valentim, DMA da Silva, VCC Capibaribe… - Behavioural Brain …, 2024 - Elsevier
The present study aimed to evaluate the protective potential of carvacrol against depressive-
like behavior and cognitive impairment prompted by chronic unpredictable mild stress …

[HTML][HTML] Ginkgo biloba supplement modulates mTOR/ERK1/2 activities to mediate cardio-protection in cyclosporin-A-induced cardiotoxicity in Wistar rats

JN Asiwe, B Ben-Azu, GD Yovwin, VJO Igben… - … Traditional Medicine and …, 2024 - Elsevier
Abstract Background Cyclosporine-A (Cs-A), an immunosuppressant drug indicated for
organ transplant patients has been associated with toxicities arising from activation of …

PERK inhibitor (ISRIB) improves depression-like behavior by inhibitions of HPA-axis over-activation in mice exposed to chronic restraint stress

L Luhong, H mao Zhou, X han Tang, J Chen… - Behavioural Brain …, 2024 - Elsevier
Stressful life event is closely associated with depression, thus strategies that blunt or prevent
the negative effect stress on the brain might benefits for the treatment of depression …

Neuromodulatory Effects Induced by the Association of Moringa oleifera Lam., Tribulus terrestris L., Rhodiola rosea Lam., and Undaria pinnatidifida Extracts in the …

A Chiavaroli, SC Di Simone, A Acquaviva… - Chemistry & …, 2024 - Wiley Online Library
The present study investigated the role of a commercial formulation constituted by herbal
extracts from Rhodiola rosea, Undaria pinnatifida, Tribulus terrestris, and Moringa oleifera …

Aromatherapy with Rosa damascena Mill. to Relieve the Symptoms of Postpartum Depression and Sleep Quality in Primiparous Women: A Randomised Controlled …

FZ Hosseini, F Behmanesh, P Mirabi… - Journal of Herbal …, 2024 - Elsevier
Introduction Postpartum depression can significantly impact mothers' health, quality of life,
and child growth and development. The present study aims to determine the effectiveness of …