Dementia is a comprehensive category of brain diseases that is great enough to affect a
person's daily functioning. The most common type of dementia is Alzheimer's disease, which …

Leishmaniasis is a vector-borne disease caused by a protozoa parasite from over 20
Leishmania species. The clinical manifestations and the outcome of the disease vary …

Despite their critical role in chronic toxoplasmosis, the biology of Toxoplasma gondii
bradyzoites is poorly understood. In an attempt to address this gap, we optimized …

Motility of pathogenic protozoa depends on flagella (synonymous with cilia) with axonemes
containing nine doublet microtubules (DMTs) and two singlet microtubules. Microtubule …

Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the
Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous …

Extracellular vesicles (EV) secreted by pathogens function in a variety of biological
processes. Here, we demonstrate that in the protozoan parasite Trypanosoma brucei …

African trypanosomes cause human African trypanosomiasis and animal African
trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most …

Signaling from ciliary microdomains controls developmental processes in metazoans.
Trypanosome transmission requires development and migration in the tsetse vector …

The unicellular parasite Trypanosoma brucei is transmitted between mammals by tsetse
flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for …

The collective movement of African trypanosomes on semi-solid surfaces, known as social
motility, is presumed to be due to migration factors and repellents released by the parasites …