Short-and medium-chain fatty acids (SCFAs and MCFAs), independently of their cellular
signaling functions, are important substrates of the energy metabolism and anabolic …

The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

Short-chain fatty acids (SCFA) are the major anion in stool and are synthesized from
nonabsorbed carbohydrate by the colonic microbiota. Nonabsorbed carbohydrate are not …

Fermentative organs such as the caecum, the colon, and the rumen have evolved to
produce and absorb energy rich short chain fatty acids (SCFA) from otherwise indigestible …

A key event featured in the early stage of chronic gut inflammatory diseases is the
disordered recruitment and excess accumulation of immune cells in the gut lamina propria …

Oral rehydration solution (ORS) was established as the cornerstone of therapy for
dehydration secondary to acute infectious diarrhea approximately 40 years ago. The efficacy …

Mutations in the human SLC26A3 gene, also known as down‐regulated in adenoma
(hDRA), cause autosomal recessive congenital chloride‐losing diarrhoea (CLD). hDRA …

Abstract The Slc9 family of Na+/H+ exchangers (NHEs) plays a critical role in electroneutral
exchange of Na+ and H+ in the mammalian intestine as well as other absorptive and …

Short-chain fatty acid (SCFA) transport across the colon may occur by nonionic diffusion
and/or via apical membrane SCFA−/HCO 3− exchange. To examine the relative importance …

Luminal isobutyrate, a relatively poor metabolized short-chain fatty acid (SCFA), induces
HCO3 secretion via a Cl-independent, DIDS-insensitive, carrier-mediated process as well as …